Tmc proteins are essential for zebrafish hearing where Tmc1 is not obligatory.

Chen, Zongwei; Zhu, Shaoyuan; Kindig, Kayla; Wang, Shengxuan; Chou, Shih-Wei; Davis, Robin Woods; Dercoli, Michael R; Weaver, Hannah; Stepanyan, Ruben; McDermott, Brian M

Chen, Zongwei; Zhu, Shaoyuan; Kindig, Kayla; Wang, Shengxuan; Chou, Shih-Wei; Davis, Robin Woods; Dercoli, Michael R; Weaver, Hannah; Stepanyan, Ruben; McDermott, Brian M.

Afiliação

Chen Z; Department of Otolaryngology-Head and Neck Surgery, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Zhu S; Department of Biology, Case Western Reserve University, Cleveland, OH 44106, USA.
Kindig K; Department of Otolaryngology-Head and Neck Surgery, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Wang S; Department of Biology, Case Western Reserve University, Cleveland, OH 44106, USA.
Chou SW; Department of Otolaryngology-Head and Neck Surgery, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Davis RW; Department of Biology, Case Western Reserve University, Cleveland, OH 44106, USA.
Dercoli MR; Department of Otolaryngology-Head and Neck Surgery, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Weaver H; Department of Biology, Case Western Reserve University, Cleveland, OH 44106, USA.
Stepanyan R; Department of Otolaryngology-Head and Neck Surgery, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
McDermott BM; Department of Biology, Case Western Reserve University, Cleveland, OH 44106, USA.

Hum Mol Genet ; 29(12): 2004-2021, 2020 07 29.

Article em En | MEDLINE | ID: mdl-32167554

Assuntos

Perda Auditiva Neurossensorial/genética; Audição/genética; Proteínas de Membrana/genética; Proteínas de Peixe-Zebra/genética; Animais; Surdez/genética; Surdez/patologia; Células Ciliadas Auditivas/metabolismo; Células Ciliadas Auditivas/patologia; Células Ciliadas Auditivas Internas/metabolismo; Células Ciliadas Auditivas Internas/patologia; Perda Auditiva Neurossensorial/patologia; Humanos; Mecanotransdução Celular/genética; Camundongos; Mutação/genética; Estereocílios/genética; Estereocílios/patologia; Peixe-Zebra/genética

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Peixe-Zebra / Audição / Perda Auditiva Neurossensorial / Proteínas de Membrana Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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