High Rates of Obesity at Presentation Persist into Survivorship across Childhood Cancer Types.
Child Obes
; 16(4): 250-257, 2020 06.
Article
em En
| MEDLINE
| ID: mdl-32176517
ABSTRACT
Background:
Subtypes of pediatric oncology patients and childhood cancer survivors who are overweight or obese have worse prognosis than their healthy-weighted peers. Several studies have examined weight status in either pediatric patients or survivors with acute leukemia, but few have compared these data across various diagnoses.Objectives:
We examined BMI from oncology diagnosis or presentation, through treatment, and into survivorship across the most common cancer types seen in pediatric oncology.Methods:
Patients were categorized into three oncologic diagnoses leukemia and lymphoma (n = 69), neural tumors (n = 80), and non-neural solid tumors (n = 80) at yearly intervals over the course of 11 years. To allow for comparisons across age groups, BMI percentiles were calculated with <5th percentile classified as underweight (n = 11), the 5th-84th percentile classified as a healthy weight (n = 129), and above the 85th percentile classified as overweight and obese (n = 87).Results:
At presentation, 45.6% of leukemia and lymphoma patients were overweight or obese, and 44.3% of neural tumor patients were overweight or obese. These high obesity rates persisted into survivorship. Compared to the non-neural tumor group, the leukemia and lymphoma group had a significant increase in BMI percentile over time, while the neural tumor group did not.Conclusions:
Pediatric patients with leukemia, lymphoma, and neural tumors and who are overweight or obese at presentation continue this trend into survivorship, indicating a need for management of overweight and obesity through lifestyle interventions concurrent with therapy.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Obesidade Infantil
/
Sobreviventes de Câncer
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Neoplasias
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article