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Synthesis and anti-inflammatory evaluation of new chalcone derivatives bearing bispiperazine linker as IL-1ß inhibitors.
Tang, Yan-Ling; Zheng, Xi; Qi, Yan; Pu, Xiao-Jia; Liu, Bei; Zhang, Xia; Li, Xiao-Si; Xiao, Wei-Lie; Wan, Chun-Ping; Mao, Ze-Wei.
Afiliação
  • Tang YL; College of Pharmaceutical Science, Yunnan University of Chinese Medicine, Kunming 650500, PR China.
  • Zheng X; Central Laboratory, The NO.1 Affiliated Hospital of Yunnan University of Chinese Medicine, Kunming 650021, PR China.
  • Qi Y; Central Laboratory, The NO.1 Affiliated Hospital of Yunnan University of Chinese Medicine, Kunming 650021, PR China.
  • Pu XJ; College of Pharmaceutical Science, Yunnan University of Chinese Medicine, Kunming 650500, PR China.
  • Liu B; College of Pharmaceutical Science, Yunnan University of Chinese Medicine, Kunming 650500, PR China.
  • Zhang X; College of Pharmaceutical Science, Yunnan University of Chinese Medicine, Kunming 650500, PR China.
  • Li XS; College of Pharmaceutical Science, Yunnan University of Chinese Medicine, Kunming 650500, PR China.
  • Xiao WL; Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education and Yunnan Province, School of Chemical Science and Technology, Yunnan University, Kunming 650091, PR China. Electronic address: xiaoweilie@ynu.edu.cn.
  • Wan CP; Central Laboratory, The NO.1 Affiliated Hospital of Yunnan University of Chinese Medicine, Kunming 650021, PR China. Electronic address: wanchunping1012@163.com.
  • Mao ZW; College of Pharmaceutical Science, Yunnan University of Chinese Medicine, Kunming 650500, PR China. Electronic address: maozw@ynutcm.edu.cn.
Bioorg Chem ; 98: 103748, 2020 05.
Article em En | MEDLINE | ID: mdl-32179281
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Chalcona / Anti-Inflamatórios não Esteroides / Interleucina-1beta / Piperazina Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Chalcona / Anti-Inflamatórios não Esteroides / Interleucina-1beta / Piperazina Idioma: En Ano de publicação: 2020 Tipo de documento: Article