Two new troponoides with anti-inflammatory activity from the stems of Juniperus formosana Hayata.
Nat Prod Res
; 35(23): 4901-4906, 2021 Dec.
Article
em En
| MEDLINE
| ID: mdl-32189528
ABSTRACT
Two new troponoides (1-2) were isolated from a 95% ethanol extract of the stems of Juniperus formosana (Cupressaceae), together with six known compounds (3-8). The structures of the new compounds were comprehensively characterized by high resolution electrospray ionization-mass spectrometry (HR-ESI-MS), 1D and 2D nuclear magnetic resonance (NMR). Compounds 1-7 were evaluated for their anti-inflammatory against the expression of IL-1ß, IL-6 and TNF-α in lipopolysaccharide (LPS)-induced RAW 264.7 macrophages. The new compounds showed moderate anti-inflammatory effect, while other compounds did show no activity.
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Base de dados:
MEDLINE
Assunto principal:
Juniperus
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article