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Design, synthesis, antitumor activity and theoretical calculation of novel PI3Ka inhibitors.
Jin, Ru-Yi; Tang, Tian; Zhou, Sha; Long, Xu; Guo, Hui; Zhou, Jing; Yan, Hao; Li, Zhi; Zuo, Zheng-Yu; Xie, Hong-Lei; Tang, Yu-Ping.
Afiliação
  • Jin RY; Shaanxi Key Lab Basic & New Herbal Medicament Research Center, College of Pharmacy, Shaanxi University of Chinese Medicine, China; Shenzhen Neptunus Medical Science and Technology Research Institute, Shenzhen, China.
  • Tang T; Shenzhen Neptunus Medical Science and Technology Research Institute, Shenzhen, China. Electronic address: candy_tangtian@163.com.
  • Zhou S; State Key Laboratory of Elemento-Organic Chemistry, Institute of Elemento-Organic Chemistry, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), College of Chemistry, Nankai University, Tianjin, China.
  • Long X; Shaanxi Key Lab Basic & New Herbal Medicament Research Center, College of Pharmacy, Shaanxi University of Chinese Medicine, China.
  • Guo H; Shaanxi Key Lab Basic & New Herbal Medicament Research Center, College of Pharmacy, Shaanxi University of Chinese Medicine, China.
  • Zhou J; Shaanxi Key Lab Basic & New Herbal Medicament Research Center, College of Pharmacy, Shaanxi University of Chinese Medicine, China.
  • Yan H; Shaanxi Key Lab Basic & New Herbal Medicament Research Center, College of Pharmacy, Shaanxi University of Chinese Medicine, China.
  • Li Z; Shaanxi Key Lab Basic & New Herbal Medicament Research Center, College of Pharmacy, Shaanxi University of Chinese Medicine, China.
  • Zuo ZY; Shaanxi Key Lab Basic & New Herbal Medicament Research Center, College of Pharmacy, Shaanxi University of Chinese Medicine, China.
  • Xie HL; Yantai Institute of Materia Medica, Yantai Key Laboratory of Nanomedicine &Advanced Preparations, Yantai, China.
  • Tang YP; Shaanxi Key Lab Basic & New Herbal Medicament Research Center, College of Pharmacy, Shaanxi University of Chinese Medicine, China. Electronic address: yupingtang@sntcm.edu.cn.
Bioorg Chem ; 98: 103737, 2020 05.
Article em En | MEDLINE | ID: mdl-32193031
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Fosfatidilinositol 3-Quinases / Teoria da Densidade Funcional / Inibidores de Fosfoinositídeo-3 Quinase Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Fosfatidilinositol 3-Quinases / Teoria da Densidade Funcional / Inibidores de Fosfoinositídeo-3 Quinase Idioma: En Ano de publicação: 2020 Tipo de documento: Article