High Mass Analysis with a Fourier Transform Ion Cyclotron Resonance Mass Spectrometer: From Inorganic Salt Clusters to Antibody Conjugates and Beyond.

Campuzano, Iain D G; Nshanian, Michael; Spahr, Christopher; Lantz, Carter; Netirojjanakul, Chawita; Li, Huilin; Wongkongkathep, Piriya; Wolff, Jeremy J; Loo, Joseph A

Campuzano, Iain D G; Nshanian, Michael; Spahr, Christopher; Lantz, Carter; Netirojjanakul, Chawita; Li, Huilin; Wongkongkathep, Piriya; Wolff, Jeremy J; Loo, Joseph A.

Afiliação

Campuzano IDG; Amgen Research, Amgen Inc, Thousand Oaks, California 91320, United States.
Nshanian M; Department of Chemistry and Biochemistry, and Department of Biological Chemistry, University of California-Los Angeles, Los Angeles, California 90095, United States.
Spahr C; Amgen Research, Amgen Inc, Thousand Oaks, California 91320, United States.
Lantz C; Department of Chemistry and Biochemistry, and Department of Biological Chemistry, University of California-Los Angeles, Los Angeles, California 90095, United States.
Netirojjanakul C; Amgen Research, Amgen Inc, Thousand Oaks, California 91320, United States.
Li H; Department of Chemistry and Biochemistry, and Department of Biological Chemistry, University of California-Los Angeles, Los Angeles, California 90095, United States.
Wongkongkathep P; Department of Chemistry and Biochemistry, and Department of Biological Chemistry, University of California-Los Angeles, Los Angeles, California 90095, United States.
Wolff JJ; Bruker Daltonics Inc, Billerica, Massachusetts 01821, United States.
Loo JA; Department of Chemistry and Biochemistry, and Department of Biological Chemistry, University of California-Los Angeles, Los Angeles, California 90095, United States.

J Am Soc Mass Spectrom ; 31(5): 1155-1162, 2020 May 06.

Article em En | MEDLINE | ID: mdl-32196330

Assuntos

Ciclotrons; Análise de Fourier; Imunoconjugados/química; Espectrometria de Massas/métodos; Sais/química; Anticorpos Monoclonais/química; Césio/química; Chaperonina 60/química; Imunoglobulina G/química; Cadeias kappa de Imunoglobulina/química; Iodetos/química; Maitansina/química; Peso Molecular; RNA Interferente Pequeno/química

Palavras-chave

Fourier transform ion cyclotron resonance; GroEL; antibody drug conjugates; cesium iodide; membrane proteins; monoclonal antibodies; nanodiscs; native-MS; siRNA

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sais / Espectrometria de Massas / Ciclotrons / Imunoconjugados / Análise de Fourier Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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