Dose dependency of Î³-H2AX formation in the rat urinary bladder treated with genotoxic and nongenotoxic bladder carcinogens.

Yamada, Takanori; Toyoda, Takeshi; Matsushita, Kohei; Morikawa, Tomomi; Ogawa, Kumiko

Yamada, Takanori; Toyoda, Takeshi; Matsushita, Kohei; Morikawa, Tomomi; Ogawa, Kumiko.

Afiliação

Yamada T; Division of Pathology, National Institute of Health Sciences, Kawasaki-ku, Kawasaki, Japan.
Toyoda T; Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology, Fuchu, Tokyo, Japan.
Matsushita K; Division of Pathology, National Institute of Health Sciences, Kawasaki-ku, Kawasaki, Japan.
Morikawa T; Division of Pathology, National Institute of Health Sciences, Kawasaki-ku, Kawasaki, Japan.
Ogawa K; Division of Pathology, National Institute of Health Sciences, Kawasaki-ku, Kawasaki, Japan.

J Appl Toxicol ; 40(9): 1219-1227, 2020 09.

Article em En | MEDLINE | ID: mdl-32203627

Assuntos

Butilidroxibutilnitrosamina/toxicidade; Carcinógenos/toxicidade; Dano ao DNA/efeitos dos fármacos; Histonas/efeitos dos fármacos; Fosfoproteínas/efeitos dos fármacos; Triazinas/toxicidade; Neoplasias da Bexiga Urinária/induzido quimicamente; Animais; Relação Dose-Resposta a Droga; Masculino; Modelos Animais; Ratos; Ratos Endogâmicos F344

Palavras-chave

N-butyl-N-(4-hydroxybutyl)nitrosamine; carcinogenicity; dose dependency; melamine; urinary bladder; Î³-H2AX

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fosfoproteínas / Triazinas / Neoplasias da Bexiga Urinária / Dano ao DNA / Butilidroxibutilnitrosamina / Carcinógenos / Histonas Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google