Combination of <i>Mycobacterium indicus pranii</i> and Heat-Induced Promastigotes Cures Drug-Resistant <i>Leishmania</i> Infection: Critical Role of Interleukin-6-Producing Classical Dendritic Cells.

Dey, Somaditya; Mukherjee, Debarati; Sultana, Sirin Salma; Mallick, Suvadip; Dutta, Aritri; Ghosh, Joydip; Hussain, Aabid; Sarkar, Biswajyoti; Mandal, Supratim; Patra, Pradyumna; Saha, Bhaskar; Pal, Chiranjib

Combination of Mycobacterium indicus pranii and Heat-Induced Promastigotes Cures Drug-Resistant Leishmania Infection: Critical Role of Interleukin-6-Producing Classical Dendritic Cells.

Dey, Somaditya; Mukherjee, Debarati; Sultana, Sirin Salma; Mallick, Suvadip; Dutta, Aritri; Ghosh, Joydip; Hussain, Aabid; Sarkar, Biswajyoti; Mandal, Supratim; Patra, Pradyumna; Saha, Bhaskar; Pal, Chiranjib.

Afiliação

Dey S; Cellular Immunology and Experimental Therapeutics Laboratory, Department of Zoology, West Bengal State University, Barasat, West Bengal, India.
Mukherjee D; Cellular Immunology and Experimental Therapeutics Laboratory, Department of Zoology, West Bengal State University, Barasat, West Bengal, India.
Sultana SS; Cellular Immunology and Experimental Therapeutics Laboratory, Department of Zoology, West Bengal State University, Barasat, West Bengal, India.
Mallick S; Cellular Immunology and Experimental Therapeutics Laboratory, Department of Zoology, West Bengal State University, Barasat, West Bengal, India.
Dutta A; Cellular Immunology and Experimental Therapeutics Laboratory, Department of Zoology, West Bengal State University, Barasat, West Bengal, India.
Ghosh J; Cellular Immunology and Experimental Therapeutics Laboratory, Department of Zoology, West Bengal State University, Barasat, West Bengal, India.
Hussain A; Cellular Immunology and Experimental Therapeutics Laboratory, Department of Zoology, West Bengal State University, Barasat, West Bengal, India.
Sarkar B; Cellular Immunology and Experimental Therapeutics Laboratory, Department of Zoology, West Bengal State University, Barasat, West Bengal, India.
Mandal S; Cellular Immunology and Experimental Therapeutics Laboratory, Department of Zoology, West Bengal State University, Barasat, West Bengal, India.
Patra P; Cellular Immunology and Experimental Therapeutics Laboratory, Department of Zoology, West Bengal State University, Barasat, West Bengal, India.
Saha B; Canning Sub-Divisional Hospital, Canning, West Bengal, India.
Pal C; National Centre for Cell Science, Pune, Maharashtra, India.

Infect Immun ; 88(6)2020 05 20.

Article em En | MEDLINE | ID: mdl-32229617

Assuntos

Proteínas de Choque Térmico/administração & dosagem; Leishmania donovani; Leishmaniose Visceral/parasitologia; Leishmaniose Visceral/terapia; Mycobacterium/fisiologia; Proteínas de Protozoários/administração & dosagem; Animais; Linfócitos T CD4-Positivos/imunologia; Linfócitos T CD4-Positivos/metabolismo; Diferenciação Celular; Terapia Combinada; Células Dendríticas/citologia; Células Dendríticas/imunologia; Células Dendríticas/metabolismo; Resistência a Medicamentos; Temperatura Alta; Memória Imunológica; Imunofenotipagem; Mediadores da Inflamação; Interleucina-6/biossíntese; Leishmania donovani/efeitos dos fármacos; Leishmania donovani/imunologia; Leishmaniose Visceral/imunologia; Leishmaniose Visceral/metabolismo; Camundongos; Mycobacterium/imunologia; Baço/imunologia; Baço/metabolismo; Baço/patologia; Subpopulações de Linfócitos T/imunologia; Subpopulações de Linfócitos T/metabolismo

Palavras-chave

Leishmania donovani; T regulatory cells; Th1-Th17; drug-resistant; memory T cells; pre-DCs and cDCs; therapeutic adjuvant

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leishmania donovani / Proteínas de Protozoários / Proteínas de Choque Térmico / Leishmaniose Visceral / Mycobacterium Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google