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Novel C-terminal heat shock protein 90 inhibitors target breast cancer stem cells and block migration, self-renewal, and epithelial-mesenchymal transition.
Subramanian, Chitra; Grogan, Patrick T; Wang, Ton; Bazzill, Joseph; Zuo, Ang; White, Peter T; Kalidindi, Avinaash; Kuszynski, Dawn; Wang, Grace; Blagg, Brian S J; Cohen, Mark S.
Afiliação
  • Subramanian C; Department of Surgery, University of Michigan, Ann Arbor, MI, USA.
  • Grogan PT; Division of Hematology, Medical Oncology, and Palliative Care, University of Wisconsin, Madison, WI, USA.
  • Wang T; Department of Surgery, University of Michigan, Ann Arbor, MI, USA.
  • Bazzill J; Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, MI, USA.
  • Zuo A; Department of Chemistry and Biochemistry, University of Notre Dame, IN, USA.
  • White PT; Department of Surgery, University of Michigan, Ann Arbor, MI, USA.
  • Kalidindi A; Department of Surgery, University of Michigan, Ann Arbor, MI, USA.
  • Kuszynski D; Department of Surgery, University of Michigan, Ann Arbor, MI, USA.
  • Wang G; Department of Pathology, University of Michigan, Ann Arbor, MI, USA.
  • Blagg BSJ; Department of Chemistry and Biochemistry, University of Notre Dame, IN, USA.
  • Cohen MS; Department of Surgery, University of Michigan, Ann Arbor, MI, USA.
Mol Oncol ; 14(9): 2058-2068, 2020 09.
Article em En | MEDLINE | ID: mdl-32255264
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco Neoplásicas / Movimento Celular / Proteínas de Choque Térmico HSP90 / Transição Epitelial-Mesenquimal / Autorrenovação Celular Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco Neoplásicas / Movimento Celular / Proteínas de Choque Térmico HSP90 / Transição Epitelial-Mesenquimal / Autorrenovação Celular Idioma: En Ano de publicação: 2020 Tipo de documento: Article