Mechanisms of neurite repair.
Curr Opin Neurobiol
; 63: 53-58, 2020 08.
Article
em En
| MEDLINE
| ID: mdl-32278210
ABSTRACT
Upon receiving injury signals, neurons can activate various pathways to reduce harm, initiate neuroprotection, and repair damaged neurite without cell death. Here, we review recent progresses in the study of neurite repair focusing on neuronal cell-autonomous mechanisms, including new findings on ion channels that serve as key regulators to initiate neurite repair and intrinsic signaling pathways and transcriptional and post-transcriptional factors that facilitate neurite repair. We also touch upon reports on how dendrites may be affected upon axotomy and how the regeneration potential in injured neurites might be maximized.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Neuritos
/
Regeneração Nervosa
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article