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Reduced C9ORF72 function exacerbates gain of toxicity from ALS/FTD-causing repeat expansion in C9orf72.
Zhu, Qiang; Jiang, Jie; Gendron, Tania F; McAlonis-Downes, Melissa; Jiang, Lulin; Taylor, Amy; Diaz Garcia, Sandra; Ghosh Dastidar, Somasish; Rodriguez, Maria J; King, Patrick; Zhang, Yongjie; La Spada, Albert R; Xu, Huaxi; Petrucelli, Leonard; Ravits, John; Da Cruz, Sandrine; Lagier-Tourenne, Clotilde; Cleveland, Don W.
Afiliação
  • Zhu Q; Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA, USA.
  • Jiang J; Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA, USA.
  • Gendron TF; Department of Cell Biology, Emory University School of Medicine, Atlanta, GA, USA.
  • McAlonis-Downes M; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.
  • Jiang L; Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA, USA.
  • Taylor A; Neuroscience Initiative, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.
  • Diaz Garcia S; Department of Neurosciences, University of California at San Diego, La Jolla, CA, USA.
  • Ghosh Dastidar S; Department of Neurosciences, University of California at San Diego, La Jolla, CA, USA.
  • Rodriguez MJ; Department of Pediatrics, University of California at San Diego, La Jolla, CA, USA.
  • King P; Molecular Neuroscience; Kasturba Medical College, Manipal Academy of Higher Education, Manipal, India.
  • Zhang Y; Department of Neurosciences, University of California at San Diego, La Jolla, CA, USA.
  • La Spada AR; Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA, USA.
  • Xu H; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.
  • Petrucelli L; Department of Pediatrics, University of California at San Diego, La Jolla, CA, USA.
  • Ravits J; Departments of Neurology, Neurobiology, and Cell Biology, Duke Center for Neurodegeneration and Neurotherapeutics, Duke University School of Medicine, Durham, NC, USA.
  • Da Cruz S; Neuroscience Initiative, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.
  • Lagier-Tourenne C; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.
  • Cleveland DW; Department of Neurosciences, University of California at San Diego, La Jolla, CA, USA.
Nat Neurosci ; 23(5): 615-624, 2020 05.
Article em En | MEDLINE | ID: mdl-32284607
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Demência Frontotemporal / Proteína C9orf72 / Esclerose Lateral Amiotrófica Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Demência Frontotemporal / Proteína C9orf72 / Esclerose Lateral Amiotrófica Idioma: En Ano de publicação: 2020 Tipo de documento: Article