Photocatalytic Oxidative Dearomatization of Orcinaldehyde Derivatives.
Org Lett
; 22(9): 3712-3716, 2020 05 01.
Article
em En
| MEDLINE
| ID: mdl-32293185
ABSTRACT
For decades, oxidative dearomatization has been employed as a key step in the synthesis of complex molecules. Challenges in controlling the chemo- and site-selectivity of this transformation have sparked the development of a variety of specialized oxidants; however, these result in stoichiometric amounts of organic byproducts. Herein, we describe a photocatalytic method for oxidative dearomatization using molecular oxygen as the stoichiometric oxidant. This provides environmentally benign entry to highly substituted o-quinols, reactive intermediates which can be elaborated to a number of natural product families.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Benzaldeídos
/
Hidroquinonas
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article