Duloxetine ameliorates the impairment of diffuse noxious inhibitory control in rat models of peripheral neuropathic pain and knee osteoarthritis pain.

Yoneda, Sosuke; Kasai, Erika; Matsuo, Midori; Tamano, Ryuta; Sakurai, Yusuke; Asaki, Toshiyuki; Fujita, Masahide

Yoneda, Sosuke; Kasai, Erika; Matsuo, Midori; Tamano, Ryuta; Sakurai, Yusuke; Asaki, Toshiyuki; Fujita, Masahide.

Afiliação

Yoneda S; Neuroscience, Laboratory for Drug Discovery and Disease Research, Shionogi & Co., Ltd., 1-1 3chome, Futaba-cho, Toyonaka, Osaka, 561-0825, Japan.
Kasai E; Neuroscience, Laboratory for Drug Discovery and Disease Research, Shionogi & Co., Ltd., 1-1 3chome, Futaba-cho, Toyonaka, Osaka, 561-0825, Japan.
Matsuo M; Neuroscience, Laboratory for Drug Discovery and Disease Research, Shionogi & Co., Ltd., 1-1 3chome, Futaba-cho, Toyonaka, Osaka, 561-0825, Japan.
Tamano R; Neuroscience, Laboratory for Drug Discovery and Disease Research, Shionogi & Co., Ltd., 1-1 3chome, Futaba-cho, Toyonaka, Osaka, 561-0825, Japan.
Sakurai Y; Neuroscience, Laboratory for Drug Discovery and Disease Research, Shionogi & Co., Ltd., 1-1 3chome, Futaba-cho, Toyonaka, Osaka, 561-0825, Japan.
Asaki T; Neuroscience, Laboratory for Drug Discovery and Disease Research, Shionogi & Co., Ltd., 1-1 3chome, Futaba-cho, Toyonaka, Osaka, 561-0825, Japan.
Fujita M; Neuroscience, Laboratory for Drug Discovery and Disease Research, Shionogi & Co., Ltd., 1-1 3chome, Futaba-cho, Toyonaka, Osaka, 561-0825, Japan. Electronic address: masahide.fujita@shionogi.co.jp.

Neurosci Lett ; 729: 134990, 2020 06 11.

Article em En | MEDLINE | ID: mdl-32315711

Assuntos

Analgésicos/farmacologia; Dor Crônica/tratamento farmacológico; Controle Inibitório Nociceptivo Difuso/efeitos dos fármacos; Cloridrato de Duloxetina/farmacologia; Osteoartrite do Joelho/tratamento farmacológico; Animais; Controle Inibitório Nociceptivo Difuso/fisiologia; Masculino; Neuralgia/tratamento farmacológico; Neuralgia/fisiopatologia; Medição da Dor/efeitos dos fármacos; Pregabalina/farmacologia; Ratos Sprague-Dawley

Palavras-chave

Celecoxib; Diffuse noxious inhibitory control; Duloxetine; Neuropathic pain; Osteoarthritis pain; Pregabalin

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Osteoartrite do Joelho / Dor Crônica / Controle Inibitório Nociceptivo Difuso / Cloridrato de Duloxetina / Analgésicos Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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