MicroRNA­431 inhibits the expression of surfactant proteins through the BMP4/activin/TGF­ß signaling pathway by targeting SMAD4.

Shen, Yan-Qing; Bao, Zhi-Dan; Pan, Jing-Jing; Mao, Xiao-Nan; Cheng, Rui; Zhou, Xiao-Guang; Zhou, Xiao-Yu; Yang, Yang

MicroRNA431 inhibits the expression of surfactant proteins through the BMP4/activin/TGFß signaling pathway by targeting SMAD4.

Shen, Yan-Qing; Bao, Zhi-Dan; Pan, Jing-Jing; Mao, Xiao-Nan; Cheng, Rui; Zhou, Xiao-Guang; Zhou, Xiao-Yu; Yang, Yang.

Afiliação

Shen YQ; Department of Neonates, Children's Hospital of Nanjing Medical University, Nanjing, Jiangsu 210008, P.R. China.
Bao ZD; Department of Neonates, Children's Hospital of Nanjing Medical University, Nanjing, Jiangsu 210008, P.R. China.
Pan JJ; Department of Pediatrics, First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China.
Mao XN; Department of Neonates, Children's Hospital of Nanjing Medical University, Nanjing, Jiangsu 210008, P.R. China.
Cheng R; Department of Neonates, Children's Hospital of Nanjing Medical University, Nanjing, Jiangsu 210008, P.R. China.
Zhou XG; Department of Neonates, Children's Hospital of Nanjing Medical University, Nanjing, Jiangsu 210008, P.R. China.
Zhou XY; Department of Neonates, Children's Hospital of Nanjing Medical University, Nanjing, Jiangsu 210008, P.R. China.
Yang Y; Department of Neonates, Children's Hospital of Nanjing Medical University, Nanjing, Jiangsu 210008, P.R. China.

Int J Mol Med ; 45(5): 1571-1582, 2020 May.

Article em En | MEDLINE | ID: mdl-32323744

Assuntos

Ativinas/genética; Proteína Morfogenética Óssea 4/genética; MicroRNAs/genética; Proteínas Associadas a Surfactantes Pulmonares/genética; Transdução de Sinais/genética; Proteína Smad4/genética; Fator de Crescimento Transformador beta/genética; Células A549; Linhagem Celular Tumoral; Regulação para Baixo/genética; Regulação da Expressão Gênica/genética; Humanos; Pulmão/metabolismo; RNA Mensageiro/genética

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Fator de Crescimento Transformador beta / Ativinas / Proteínas Associadas a Surfactantes Pulmonares / MicroRNAs / Proteína Smad4 / Proteína Morfogenética Óssea 4 Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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