Flipping the Switch: Homeostatic Tuning of Chandelier Synapses Follows Developmental Changes in GABA Polarity.
Neuron
; 106(2): 199-201, 2020 04 22.
Article
em En
| MEDLINE
| ID: mdl-32325052
ABSTRACT
Homeostatic plasticity rules are well described for glutamatergic synapses but less clear for GABAergic synapses. In this issue of Neuron, Pan-Vazquez et al. (2020) leverage the precise targeting of chandelier-to-pyramidal cell connectivity to understand how homeostatic plasticity regulates GABAergic synapses, showing that these synapses maintain homeostatic rules even as they flip from exciting to inhibiting pyramidal cells.
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1
Base de dados:
MEDLINE
Assunto principal:
Segmento Inicial do Axônio
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article