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Selected ellipticine derivatives, known to target topoisomerase II, suppress the alternative lengthening of telomere (ALT) pathway in telomerase-negative cells.
Zencir, Sevil; Hsieh, Meng-Hsun; Hsu, Joel-Sean; Ergun, Yavuz; Chou, Guan-Ling; Li, Tsai-Kun; Teng, Shu-Chun; Topcu, Zeki.
Afiliação
  • Zencir S; Department of Molecular Biology, University of Geneva, CH-1211, Geneva 4, Switzerland. sevil.zencir@unige.ch.
  • Hsieh MH; Department of Medical Biology, Faculty of Medicine, Pamukkale University, 20020, Denizli, Turkey. sevil.zencir@unige.ch.
  • Hsu JS; Department of Microbiology, College of Medicine, National Taiwan University, Taipei, 10051, Taiwan.
  • Ergun Y; Department of Microbiology, College of Medicine, National Taiwan University, Taipei, 10051, Taiwan.
  • Chou GL; Department of Chemistry, Faculty of Science, Dokuz Eylul University, 35160, Izmir, Turkey.
  • Li TK; Department of Microbiology, College of Medicine, National Taiwan University, Taipei, 10051, Taiwan.
  • Teng SC; Department of Microbiology, College of Medicine, National Taiwan University, Taipei, 10051, Taiwan.
  • Topcu Z; Department of Microbiology, College of Medicine, National Taiwan University, Taipei, 10051, Taiwan.
J Cancer Res Clin Oncol ; 146(7): 1671-1676, 2020 Jul.
Article em En | MEDLINE | ID: mdl-32333143
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Telomerase / Elipticinas / Inibidores da Topoisomerase II / Homeostase do Telômero / Antineoplásicos Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Telomerase / Elipticinas / Inibidores da Topoisomerase II / Homeostase do Telômero / Antineoplásicos Idioma: En Ano de publicação: 2020 Tipo de documento: Article