Novel triphenylamine-based fluorescent chemo-sensors for fast detection of thiophenols in vitro and in vivo.
Spectrochim Acta A Mol Biomol Spectrosc
; 236: 118348, 2020 Aug 05.
Article
em En
| MEDLINE
| ID: mdl-32334384
ABSTRACT
A novel chemo-sensor based on triphenylamine derivative Probe-TPA for thiophenols (C6H5SH, p-NH2-C6H4SH, p-OH-C6H4SH) detection was presented in this work. The target dye Probe-TPA displayed high selectivity and extremely fast response toward thiophenols in DMSO/PBS buffer (5/5, v/v) solution in the presence of other competitive species (such as K+, Na+, Ni2+, Fe3+, S2-, HS-, SO42-, SO32-, NaClO, H2O2, GSH, Cys, Hcy, etc.). The sensing property for thiophenols was studied by UV-Visible, fluorescence spectrophotometric analyses and DFT/TD-DFT calculations, those results indicated that the sensor Probe-TPA possessed high anti-interference ability, excellent sensitivity, higher specifity, dramatically "naked-eye" fluorescence enhancement (almost 200-folds) under 365 nm UV lamp, especially immediate response speed (within 15 s). In extended application aspect, the fluorescent chemo-sensor Probe-TPA could provide a new method of analysis to detect of thiophenol in real water samples and visualize monitoring in live cells with remarkable fluorescence variation.
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MEDLINE
Assunto principal:
Fenóis
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Compostos de Sulfidrila
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Poluentes Químicos da Água
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Corantes Fluorescentes
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En
Ano de publicação:
2020
Tipo de documento:
Article