Identification of organophosphorus insecticides and their hydrolysis products by liquid chromatography in combination with UV and thermospray-mass spectrometric detection.
J Chromatogr
; 455: 163-72, 1988 Nov 25.
Article
em En
| MEDLINE
| ID: mdl-3235610
ABSTRACT
Liquid chromatography with ultraviolet detection (LC-UV) and positive and negative ion mode (PI and NI, respectively) thermospray LC-mass spectrometry (LC-MS) were used for the analysis of the organophosphorus pesticides azinphos-methyl, diazinon and parathion-methyl and their corresponding breakdown products obtained after basic hydrolysis (pH 7-11). LC analysis was performed in the reversed-phase mode using methanol-water (8020) or methanol-water (7030) + 0.1 M ammonium acetate for LC-UV or LC-MS, respectively. By employing NI thermospray LC-MS the identification of p-nitrophenol, showing the [2M-H]- ion as the base peak, was feasible and confirmed the LC-UV chromatogram at 220 nm. When the PI mode was used, [M + NH4]+ and [M + H]+ ions were obtained as base peaks for azinphos-methyl and diazinon, respectively. The degradation rates varied from diazinon, which showed no degradation during a period of ten days, to azinphos-methyl and parathion-methyl, for which degradation occurred rapidly when the pH was increased from 7 to 11.
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Base de dados:
MEDLINE
Assunto principal:
Paration
/
Azinfos-Metil
/
Diazinon
/
Inseticidas
/
Metil Paration
Idioma:
En
Ano de publicação:
1988
Tipo de documento:
Article