Mitochondrial DNA control region variation in a population sample from Thailand.
Int J Legal Med
; 134(5): 1563-1568, 2020 Sep.
Article
em En
| MEDLINE
| ID: mdl-32358724
ABSTRACT
Mitochondrial DNA (mtDNA) control region sequences from hair samples of 213 individuals from Thailand were analyzed using Sanger sequencing. A total of 170 different haplotypes were identified, of which 146 occurred only once (unique haplotypes). The dataset showed a random match probability of 0.87% and a haplotype diversity of 0.9960. The samples were assigned to 85 different haplogroups with B5a, F1a1a, and M being the most frequent ones. Pairwise FST-values between this and other Southeast and East Asian populations revealed significant but relatively low differences, indicating a close relation. Heteroplasmic positions were observed in 12.2% of hair samples confirming the frequent appearance of heteroplasmic positions in hairs. This dataset will complement existing data as an mtDNA reference for forensic investigations.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Haplótipos
/
DNA Mitocondrial
/
Etnicidade
/
Região de Controle de Locus Gênico
/
Povo Asiático
/
Cabelo
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article