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Mitochondrial DNA control region variation in a population sample from Thailand.
Sauer, Dirk Christopher; Naue, Jana; Immel, Uta-Dorothee; Lutz-Bonengel, Sabine.
Afiliação
  • Sauer DC; Institute of Forensic Medicine, Medical Center - University of Freiburg, Forensic Molecular Biology, Albertstrasse 9, 79104, Freiburg, Germany.
  • Naue J; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Immel UD; Institute of Forensic Medicine, Medical Center - University of Freiburg, Forensic Molecular Biology, Albertstrasse 9, 79104, Freiburg, Germany.
  • Lutz-Bonengel S; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Int J Legal Med ; 134(5): 1563-1568, 2020 Sep.
Article em En | MEDLINE | ID: mdl-32358724
ABSTRACT
Mitochondrial DNA (mtDNA) control region sequences from hair samples of 213 individuals from Thailand were analyzed using Sanger sequencing. A total of 170 different haplotypes were identified, of which 146 occurred only once (unique haplotypes). The dataset showed a random match probability of 0.87% and a haplotype diversity of 0.9960. The samples were assigned to 85 different haplogroups with B5a, F1a1a, and M being the most frequent ones. Pairwise FST-values between this and other Southeast and East Asian populations revealed significant but relatively low differences, indicating a close relation. Heteroplasmic positions were observed in 12.2% of hair samples confirming the frequent appearance of heteroplasmic positions in hairs. This dataset will complement existing data as an mtDNA reference for forensic investigations.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Haplótipos / DNA Mitocondrial / Etnicidade / Região de Controle de Locus Gênico / Povo Asiático / Cabelo Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Haplótipos / DNA Mitocondrial / Etnicidade / Região de Controle de Locus Gênico / Povo Asiático / Cabelo Idioma: En Ano de publicação: 2020 Tipo de documento: Article