ß-Carotene and its physiological metabolites: Effects on oxidative status regulation and genotoxicity in in vitro models.

Ribeiro, Daniela; Sousa, Adelaide; Nicola, Pedro; Ferreira de Oliveira, José Miguel P; Rufino, Ana T; Silva, Marta; Freitas, Marisa; Carvalho, Félix; Fernandes, Eduarda

Ribeiro, Daniela; Sousa, Adelaide; Nicola, Pedro; Ferreira de Oliveira, José Miguel P; Rufino, Ana T; Silva, Marta; Freitas, Marisa; Carvalho, Félix; Fernandes, Eduarda.

Afiliação

Ribeiro D; LAQV, REQUIMTE, Laboratory of Applied Chemistry, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, Porto, Portugal. Electronic address: dsribeiro@ff.up.pt.
Sousa A; LAQV, REQUIMTE, Laboratory of Applied Chemistry, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, Porto, Portugal.
Nicola P; LAQV, REQUIMTE, Laboratory of Applied Chemistry, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, Porto, Portugal.
Ferreira de Oliveira JMP; LAQV, REQUIMTE, Laboratory of Applied Chemistry, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, Porto, Portugal.
Rufino AT; LAQV, REQUIMTE, Laboratory of Applied Chemistry, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, Porto, Portugal.
Silva M; LAQV, REQUIMTE, Laboratory of Applied Chemistry, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, Porto, Portugal.
Freitas M; LAQV, REQUIMTE, Laboratory of Applied Chemistry, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, Porto, Portugal.
Carvalho F; UCIBIO, REQUIMTE, Laboratory of Toxicology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, Porto, Portugal.
Fernandes E; LAQV, REQUIMTE, Laboratory of Applied Chemistry, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, Porto, Portugal. Electronic address: egracas@ff.up.pt.

Food Chem Toxicol ; 141: 111392, 2020 Jul.

Article em En | MEDLINE | ID: mdl-32360219

Assuntos

Estresse Oxidativo/efeitos dos fármacos; beta Caroteno/metabolismo; Humanos; Técnicas In Vitro; Testes de Mutagenicidade; beta Caroteno/farmacologia

Palavras-chave

Genotoxicity; Lipid peroxidation; Reactive species; trans-ß-Apo-8'-carotenal; ß-Carotene; ß-Ionone

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Estresse Oxidativo / Beta Caroteno Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Estresse Oxidativo / Beta Caroteno Idioma: En Ano de publicação: 2020 Tipo de documento: Article