Inhibition of UDP-glucuronosyltransferases by different furoquinoline alkaloids.

Li, Yixuan; Zhang, Weihua; Yin, Tingting; Wang, Ce; Wang, Feige; Sun, Jing; Liu, Lina; Zhang, Qinghuai; Zhang, Chunze

Li, Yixuan; Zhang, Weihua; Yin, Tingting; Wang, Ce; Wang, Feige; Sun, Jing; Liu, Lina; Zhang, Qinghuai; Zhang, Chunze.

Afiliação

Li Y; School of integrative medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Zhang W; Department of Colorectal Surgery, Tianjin Union Medical Center, Tianjin, China.
Yin T; Department of Colorectal Surgery, Tianjin Union Medical Center, Tianjin, China.
Wang C; School of integrative medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Wang F; Department of Colorectal Surgery, Tianjin Union Medical Center, Tianjin, China.
Sun J; Basic Medical College, Hebei North University, Hebei, China.
Liu L; School of integrative medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Zhang Q; Department of Colorectal Surgery, Tianjin Union Medical Center, Tianjin, China.
Zhang C; Department of Colorectal Surgery, Tianjin Union Medical Center, Tianjin, China.

Xenobiotica ; 50(10): 1170-1179, 2020 Oct.

Article em En | MEDLINE | ID: mdl-32367776

Assuntos

Inibidores Enzimáticos/metabolismo; Glucuronosiltransferase/metabolismo; Himecromona/metabolismo; Alcaloides; Simulação por Computador; Interações Ervas-Drogas; Humanos; Simulação de Acoplamento Molecular; Quinolinas

Palavras-chave

Furoquinoline alkaloids; UDP-glucuronosyltransferases (UGTs); dictamnine; haplopine; herbdrug interactions (HDIs); skimmianine; Î³-fagarine

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Himecromona / Glucuronosiltransferase / Inibidores Enzimáticos Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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