Cysteine cathepsins L and X differentially modulate interactions between myeloid-derived suppressor cells and tumor cells.

Jakos, Tanja; Pislar, Anja; Pecar Fonovic, Ursa; Svajger, Urban; Kos, Janko

Jakos, Tanja; Pislar, Anja; Pecar Fonovic, Ursa; Svajger, Urban; Kos, Janko.

Afiliação

Jakos T; Department of Pharmaceutical Biology, Faculty of Pharmacy, University of Ljubljana, Askerceva cesta 7, 1000, Ljubljana, Slovenia.
Pislar A; Department of Pharmaceutical Biology, Faculty of Pharmacy, University of Ljubljana, Askerceva cesta 7, 1000, Ljubljana, Slovenia.
Pecar Fonovic U; Department of Pharmaceutical Biology, Faculty of Pharmacy, University of Ljubljana, Askerceva cesta 7, 1000, Ljubljana, Slovenia.
Svajger U; Department for Therapeutic Services, Blood Transfusion Centre of Slovenia, Ljubljana, Slovenia.
Kos J; Department of Pharmaceutical Biology, Faculty of Pharmacy, University of Ljubljana, Askerceva cesta 7, 1000, Ljubljana, Slovenia. janko.kos@ffa.uni-lj.si.

Cancer Immunol Immunother ; 69(9): 1869-1880, 2020 Sep.

Article em En | MEDLINE | ID: mdl-32372139

Assuntos

Catepsina L/metabolismo; Cisteína/metabolismo; Células Supressoras Mieloides/metabolismo; Neoplasias/metabolismo; Linfócitos T CD8-Positivos/imunologia; Linhagem Celular Tumoral; Humanos; Leucócitos Mononucleares/metabolismo; Invasividade Neoplásica/patologia; Neoplasias/patologia; Células PC-3

Palavras-chave

Cancer; Cathepsin inhibition; Cysteine cathepsins; Immunosuppression; MDA-MB-231 cells; Myeloid-derived suppressor cells

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cisteína / Catepsina L / Células Supressoras Mieloides / Neoplasias Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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