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Preclinical validation of a repurposed metal chelator as an early-intervention therapeutic for hemotoxic snakebite.
Albulescu, Laura-Oana; Hale, Melissa S; Ainsworth, Stuart; Alsolaiss, Jaffer; Crittenden, Edouard; Calvete, Juan J; Evans, Chloe; Wilkinson, Mark C; Harrison, Robert A; Kool, Jeroen; Casewell, Nicholas R.
Afiliação
  • Albulescu LO; Centre for Snakebite Research and Interventions, Liverpool School of Tropical Medicine, Pembroke Place, L3 5QA Liverpool, UK.
  • Hale MS; Centre for Snakebite Research and Interventions, Liverpool School of Tropical Medicine, Pembroke Place, L3 5QA Liverpool, UK.
  • Ainsworth S; Centre for Snakebite Research and Interventions, Liverpool School of Tropical Medicine, Pembroke Place, L3 5QA Liverpool, UK.
  • Alsolaiss J; Centre for Snakebite Research and Interventions, Liverpool School of Tropical Medicine, Pembroke Place, L3 5QA Liverpool, UK.
  • Crittenden E; Centre for Snakebite Research and Interventions, Liverpool School of Tropical Medicine, Pembroke Place, L3 5QA Liverpool, UK.
  • Calvete JJ; Laboratorio de Venómica Estructural y Funcional, Instituto de Biomedicina de Valencia, CSIC, Valencia 46010, Spain.
  • Evans C; Centre for Snakebite Research and Interventions, Liverpool School of Tropical Medicine, Pembroke Place, L3 5QA Liverpool, UK.
  • Wilkinson MC; Centre for Snakebite Research and Interventions, Liverpool School of Tropical Medicine, Pembroke Place, L3 5QA Liverpool, UK.
  • Harrison RA; Centre for Snakebite Research and Interventions, Liverpool School of Tropical Medicine, Pembroke Place, L3 5QA Liverpool, UK.
  • Kool J; Centre for Drugs and Diagnostics, Liverpool School of Tropical Medicine, Pembroke Place, L3 5QA Liverpool, UK.
  • Casewell NR; Amsterdam Institute for Molecules Medicines and Systems, Division of BioAnalytical Chemistry, Department of Chemistry and Pharmaceutical Sciences, Faculty of Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1083, 1081HV Amsterdam, Netherlands.
Sci Transl Med ; 12(542)2020 05 06.
Article em En | MEDLINE | ID: mdl-32376771
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Mordeduras de Serpentes Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Mordeduras de Serpentes Idioma: En Ano de publicação: 2020 Tipo de documento: Article