Blood microparticles are a component of immune modulation in red blood cell transfusion.
Eur J Immunol
; 50(8): 1237-1240, 2020 08.
Article
em En
| MEDLINE
| ID: mdl-32379351
ABSTRACT
Patients may display alloimmunization following transfusion. Microparticles (MPs) released into the blood are present in transfusion products. We show that MPs can modulate the immune system, CD4+ T-cell, and humoral responses, through their concentration, cellular origin and phenotype, and should therefore be considered to reduce the immune impact of transfusion.
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Base de dados:
MEDLINE
Assunto principal:
Transfusão de Eritrócitos
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Eritrócitos
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Micropartículas Derivadas de Células
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Imunomodulação
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article