[Full thickness resection of a pyloric adenoma in the proximal duodenum in a 67-year-old patient with attenuated polyposis coli]. / Vollwandresektion eines Pylorusdrüsenadenoms im proximalen Duodenum bei einem 67-jährigen Patienten mit attenuierter Polyposis coli.
Z Gastroenterol
; 58(8): 767-772, 2020 Aug.
Article
em De
| MEDLINE
| ID: mdl-32380553
ABSTRACT
BACKGROUND:
Pyloric gland adenomas (PGAs) are very rare and underdiagnosed, mostly be founded in the stomach. Similar to colorectal adenomas they have a high risk of malignant transformation to adenocarcinoma up to 12-47â%. Endoscopic resections in the duodenum harbor a significant risk of complications. EMR is the current standard technique for treatment of duodenal non-ampullary adenomas. Complete resection rates are considerably high at about 90â%. Adverse events as bleeding was reported up to 25â%. ESD is not recommended for resection of duodenal lesions since the perforation rate may be as high as 35â%. Use of EFTR in the duodenum are limited to a single case study of 20 patients. CASE A 67 year old patient with attenuated polyposis coli presented for screening. Gastroscopy showed a 20âmm large, non-ampullary lesions in the proximal duodenum (pars I). The margins of the duodenal lesions were marked with a high-frequency (HF) probe. An integrated balloon dilatation (20âmm) of the upper esophageal sphincter and the pylorus was performed to facilitate advancing of the gastroduodenal FTRD® (Ovesco Endoscopy AG). After pulling the duodenal lesion into the cap with a grasper the FTRD clip was deployed and the lesion immediately resected with the preloaded snare. A single-shot antibiotic prophylaxis with 2âg ceftriaxone i.âv. was administered during the intervention. Second-look endoscopy was scheduled 24âh after resection. The resectat showed histologically a gastric type adenoma of 18âmm in the proximal duodenum (immunohistochemistry positive for Mucin-1, Mucin-5, Mib 1).CONCLUSION:
Herein we present the first case of duodenal EFTR in a patient with attenuated FAP and a PGA. There are currently no specific guidelines for the removal and surveillance. ASGE recommends resection and surveillance endoscopy at 3-5 years interval.
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Adenoma
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Duodenoscopia
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Polipose Adenomatosa do Colo
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Neoplasias Duodenais
Idioma:
De
Ano de publicação:
2020
Tipo de documento:
Article