[Esophagogastric Junctional Adenocarcinoma Responding Completely to Chemotherapy in an Elderly Patient with Long-Term Survival and No Recurrences-A Case Report].
Gan To Kagaku Ryoho
; 47(1): 105-107, 2020 Jan.
Article
em Ja
| MEDLINE
| ID: mdl-32381873
An 85-year-old man was diagnosed with esophagogastric junctional adenocarcinoma, E=G, Type 2, por, 6 cm in size, cT4aN1M0, cStage â
¢A. He had a history of atherosclerosis obliterans and thoracoabdominal aortic aneurysm. Considering the comorbidities and life expectancy, we decided to perform chemotherapy without tumor resection. Although the renal function was poor, we chose SP therapy(S-1 80mg/kg/day for 14 days, followed by 7-day rest, CDDP 30mg/kg/day on day 1)because the current status of the patient was satisfactory. The primary tumor remarkably shrank after 2 courses of SP therapy and completely disappeared after 5 courses of SP therapy. There were no adverse events during the entire course of treatment. We detected clinical CR and provided the S-1 monotherapy for another 2 years. The patient has survived with no recurrences for 7 years since the initial chemotherapy. Although intensive chemotherapy regimens are avoided in elderly patients, the patient, in this case, showed a favorable prognosis from powerful chemotherapy.
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Base de dados:
MEDLINE
Assunto principal:
Neoplasias Gástricas
/
Adenocarcinoma
Idioma:
Ja
Ano de publicação:
2020
Tipo de documento:
Article