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Development of a Conformational Histamine H3 Receptor Biosensor for the Synchronous Screening of Agonists and Inverse Agonists.
Schihada, Hannes; Ma, Xiaoyuan; Zabel, Ulrike; Vischer, Henry F; Schulte, Gunnar; Leurs, Rob; Pockes, Steffen; Lohse, Martin J.
Afiliação
  • Schihada H; Section of Receptor Biology & Signaling, Dept. Physiology & Pharmacology, Karolinska Institutet, Stockholm 171 77, Sweden.
  • Ma X; Institute of Pharmacology and Toxicology and Rudolf Virchow Center, University of Würzburg, Würzburg 97070, Germany.
  • Zabel U; Amsterdam Institute for Molecules, Medicines and Systems, Division of Medicinal Chemistry, Faculty of Science, Vrije Universiteit Amsterdam, Amsterdam 1081 HV, The Netherlands.
  • Vischer HF; Institute of Pharmacology and Toxicology and Rudolf Virchow Center, University of Würzburg, Würzburg 97070, Germany.
  • Schulte G; Amsterdam Institute for Molecules, Medicines and Systems, Division of Medicinal Chemistry, Faculty of Science, Vrije Universiteit Amsterdam, Amsterdam 1081 HV, The Netherlands.
  • Leurs R; Section of Receptor Biology & Signaling, Dept. Physiology & Pharmacology, Karolinska Institutet, Stockholm 171 77, Sweden.
  • Pockes S; Amsterdam Institute for Molecules, Medicines and Systems, Division of Medicinal Chemistry, Faculty of Science, Vrije Universiteit Amsterdam, Amsterdam 1081 HV, The Netherlands.
  • Lohse MJ; Institute of Pharmacy, Faculty of Chemistry and Pharmacy, University of Regensburg, Regensburg 93053, Germany.
ACS Sens ; 5(6): 1734-1742, 2020 06 26.
Article em En | MEDLINE | ID: mdl-32397705
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Técnicas Biossensoriais / Receptores Histamínicos H3 Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Técnicas Biossensoriais / Receptores Histamínicos H3 Idioma: En Ano de publicação: 2020 Tipo de documento: Article