Proteoglycan-4 regulates fibroblast to myofibroblast transition and expression of fibrotic genes in the synovium.

Qadri, Marwa; Jay, Gregory D; Zhang, Ling X; Richendrfer, Holly; Schmidt, Tannin A; Elsaid, Khaled A

Qadri, Marwa; Jay, Gregory D; Zhang, Ling X; Richendrfer, Holly; Schmidt, Tannin A; Elsaid, Khaled A.

Afiliação

Qadri M; Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, Rinker Health Sciences Campus, 9401 Jeronimo Road, Irvine, CA, 92618, USA.
Jay GD; Department of Pharmacology, College of Pharmacy, Jazan University, Jazan, 82826, Saudi Arabia.
Zhang LX; Department of Emergency Medicine, Rhode Island Hospital, Providence, RI, USA.
Richendrfer H; Department of Emergency Medicine, Rhode Island Hospital, Providence, RI, USA.
Schmidt TA; Department of Emergency Medicine, Rhode Island Hospital, Providence, RI, USA.
Elsaid KA; Biomedical Engineering Department, School of Dental Medicine, University of Connecticut, Farmington, CT, USA.

Arthritis Res Ther ; 22(1): 113, 2020 05 13.

Article em En | MEDLINE | ID: mdl-32404156

Assuntos

Diferenciação Celular; Miofibroblastos/citologia; Proteoglicanas/genética; Membrana Sinovial; Idoso; Animais; Feminino; Fibroblastos; Fibrose; Humanos; Receptores de Hialuronatos; Masculino; Camundongos; Camundongos Knockout; Pessoa de Meia-Idade; Células NIH 3T3

Palavras-chave

CD44; Myofibroblast; Proteoglycan-4; SMA; Synovial fibrosis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteoglicanas / Membrana Sinovial / Diferenciação Celular / Miofibroblastos Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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