Membrane Association Transforms an Inert Anti-TCRß Fab' Ligand into a Potent T Cell Receptor Agonist.

Lin, Jenny J; O'Donoghue, Geoff P; Wilhelm, Kiera B; Coyle, Michael P; Low-Nam, Shalini T; Fay, Nicole C; Alfieri, Katherine N; Groves, Jay T

Lin, Jenny J; O'Donoghue, Geoff P; Wilhelm, Kiera B; Coyle, Michael P; Low-Nam, Shalini T; Fay, Nicole C; Alfieri, Katherine N; Groves, Jay T.

Afiliação

Lin JJ; Department of Chemistry, University of California, Berkeley, Berkeley, California.
O'Donoghue GP; Department of Chemistry, University of California, Berkeley, Berkeley, California. Electronic address: geoff.odonoghue@gmail.com.
Wilhelm KB; Department of Chemistry, University of California, Berkeley, Berkeley, California.
Coyle MP; Department of Chemistry, University of California, Berkeley, Berkeley, California. Electronic address: coylem6@gmail.com.
Low-Nam ST; Department of Chemistry, University of California, Berkeley, Berkeley, California.
Fay NC; Department of Molecular and Cellular Biology, University of California, Berkeley, Berkeley, California.
Alfieri KN; Department of Chemistry, University of California, Berkeley, Berkeley, California.
Groves JT; Department of Chemistry, University of California, Berkeley, Berkeley, California. Electronic address: jtgroves@lbl.gov.

Biophys J ; 118(12): 2879-2893, 2020 06 16.

Article em En | MEDLINE | ID: mdl-32407684

Assuntos

Ativação Linfocitária; Receptores de Antígenos de Linfócitos T; Animais; Ligantes; Complexo Principal de Histocompatibilidade; Camundongos; Linfócitos T

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ativação Linfocitária / Receptores de Antígenos de Linfócitos T Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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