An Innovative Sequence-to-Structure-Based Approach to Drug Resistance Interpretation and Prediction: The Use of Molecular Interaction Fields to Detect HIV-1 Protease Binding-Site Dissimilarities.

Alves, Nuno G; Mata, Ana I; Luís, João P; Brito, Rui M M; Simões, Carlos J V

Alves, Nuno G; Mata, Ana I; Luís, João P; Brito, Rui M M; Simões, Carlos J V.

Afiliação

Alves NG; Department of Chemistry, Coimbra Chemistry Centre, University of Coimbra, Coimbra, Portugal.
Mata AI; Department of Chemistry, Coimbra Chemistry Centre, University of Coimbra, Coimbra, Portugal.
Luís JP; Department of Chemistry, Coimbra Chemistry Centre, University of Coimbra, Coimbra, Portugal.
Brito RMM; Department of Chemistry, Coimbra Chemistry Centre, University of Coimbra, Coimbra, Portugal.
Simões CJV; BSIM Therapeutics, Instituto Pedro Nunes, Coimbra, Portugal.

Front Chem ; 8: 243, 2020.

Article em En | MEDLINE | ID: mdl-32411655