Rno-microRNA-30c-5p promotes myocardial ischemia reperfusion injury in rats through activating NF-&#954;B pathway and targeting SIRT1.

Chen, Jianfeng; Zhang, Mingming; Zhang, Shouyan; Wu, Junlong; Xue, Shufeng

Rno-microRNA-30c-5p promotes myocardial ischemia reperfusion injury in rats through activating NF-κB pathway and targeting SIRT1.

Chen, Jianfeng; Zhang, Mingming; Zhang, Shouyan; Wu, Junlong; Xue, Shufeng.

Afiliação

Chen J; Department of Cardiology, Luoyang Central Hospital Affiliated to Zhengzhou University, No. 288, Zhongzhou Middle Road, Luoyang City, 471000, Henan Province, China.
Zhang M; Department of Cardiology, Luoyang Central Hospital Affiliated to Zhengzhou University, No. 288, Zhongzhou Middle Road, Luoyang City, 471000, Henan Province, China.
Zhang S; Department of Cardiology, Luoyang Central Hospital Affiliated to Zhengzhou University, No. 288, Zhongzhou Middle Road, Luoyang City, 471000, Henan Province, China. zgangshouyan289@163.com.
Wu J; Department of Orthopedics, Luoyang Central Hospital Affiliated to Zhengzhou University, No. 288, Zhongzhou Middle Road, Luoyang City, 471000, Henan Province, China.
Xue S; Department of Cardiology, Luoyang Central Hospital Affiliated to Zhengzhou University, No. 288, Zhongzhou Middle Road, Luoyang City, 471000, Henan Province, China.

BMC Cardiovasc Disord ; 20(1): 240, 2020 05 20.

Article em En | MEDLINE | ID: mdl-32434515

Assuntos

MicroRNAs/metabolismo; Infarto do Miocárdio/enzimologia; Traumatismo por Reperfusão Miocárdica/enzimologia; Miocárdio/enzimologia; NF-kappa B/metabolismo; Sirtuína 1/metabolismo; Animais; Apoptose; Células Cultivadas; Citocinas/metabolismo; Modelos Animais de Doenças; Mediadores da Inflamação/metabolismo; Masculino; MicroRNAs/genética; Infarto do Miocárdio/genética; Infarto do Miocárdio/patologia; Traumatismo por Reperfusão Miocárdica/genética; Traumatismo por Reperfusão Miocárdica/patologia; Miocárdio/patologia; Ratos Sprague-Dawley; Transdução de Sinais; Sirtuína 1/genética

Palavras-chave

Apoptosis; Inflammation; Myocardial ischemia reperfusion injury; NF-κB pathway; Rno-miR-30c-5p; SIRT1

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Traumatismo por Reperfusão Miocárdica / NF-kappa B / MicroRNAs / Sirtuína 1 / Infarto do Miocárdio / Miocárdio Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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