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Selective inhibition of glycogen synthase kinase 3α corrects pathophysiology in a mouse model of fragile X syndrome.
McCamphill, Patrick K; Stoppel, Laura J; Senter, Rebecca K; Lewis, Michael C; Heynen, Arnold J; Stoppel, David C; Sridhar, Vinay; Collins, Katie A; Shi, Xi; Pan, Jen Q; Madison, Jon; Cottrell, Jeffrey R; Huber, Kimberly M; Scolnick, Edward M; Holson, Edward B; Wagner, Florence F; Bear, Mark F.
Afiliação
  • McCamphill PK; Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Stoppel LJ; Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Senter RK; Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Lewis MC; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Heynen AJ; Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Stoppel DC; Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Sridhar V; University of Texas Southwestern Medical Center, Department of Neuroscience, Dallas, TX 75390, USA.
  • Collins KA; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Shi X; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Pan JQ; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Madison J; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Cottrell JR; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Huber KM; University of Texas Southwestern Medical Center, Department of Neuroscience, Dallas, TX 75390, USA.
  • Scolnick EM; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Holson EB; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Wagner FF; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. mbear@mit.edu fwagner@broadinstitute.org.
  • Bear MF; Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. mbear@mit.edu fwagner@broadinstitute.org.
Sci Transl Med ; 12(544)2020 05 20.
Article em En | MEDLINE | ID: mdl-32434848
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Síndrome do Cromossomo X Frágil Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Síndrome do Cromossomo X Frágil Idioma: En Ano de publicação: 2020 Tipo de documento: Article