Single low-dose ofloxacin for the treatment of uncomplicated urinary tract infection in young women.
J Antimicrob Chemother
; 22(6): 945-9, 1988 Dec.
Article
em En
| MEDLINE
| ID: mdl-3243742
ABSTRACT
Fifty premenopausal women with uncomplicated urinary tract infection (UTI) were treated with a single dose of 100 mg of ofloxacin. Duration of symptoms before the treatment, number of episodes of UTI during the last year, association with sexual activity, and the use of contraceptives were evaluated in relation to the clinical and microbiological response. Forty-seven women (94%) were cured clinically and microbiologically three days after treatment. Follow up at 28 days disclosed that 43 (86%) were free of symptoms and in 40 (80%) the urinary cultures were negative. Significantly higher rates of microbiological failure or reinfection were found among women with three or more episodes of UTI during the last year. This study shows that a single dose of ofloxacin is effective for therapy of uncomplicated UTI in young women.
Palavras-chave
Antibiotics--administraction and dosage; Asia; Biology; Contraception; Contraceptive Usage; Developed Countries; Diseases; Drugs; Evaluation; Examinations And Diagnoses; Family Planning; Follow-up Studies; Infections; Israel; Laboratory Examinations And Diagnoses; Mediterranean Countries; Physiology; Research Methodology; Studies; Treatment; Urogenital Effects; Urogenital System; Western Asia
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Base de dados:
MEDLINE
Assunto principal:
Infecções Urinárias
/
Ofloxacino
Idioma:
En
Ano de publicação:
1988
Tipo de documento:
Article