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Agonist of RORA Attenuates Nonalcoholic Fatty Liver Progression in Mice via Up-regulation of MicroRNA 122.
Chai, Chofit; Cox, Bryan; Yaish, Dayana; Gross, Devora; Rosenberg, Nofar; Amblard, Franck; Shemuelian, Zohar; Gefen, Maytal; Korach, Amit; Tirosh, Oren; Lanton, Tali; Link, Henrike; Tam, Joseph; Permyakova, Anna; Ozhan, Gunes; Citrin, Jonathan; Liao, Haixing; Tannous, Mirna; Hahn, Michal; Axelrod, Jonathan; Arretxe, Enara; Alonso, Cristina; Martinez-Arranz, Ibon; Betés, Pablo Ortiz; Safadi, Rifaat; Salhab, Ahmad; Amer, Johnny; Tber, Zahira; Mengshetti, Seema; Giladi, Hilla; Schinazi, Raymond F; Galun, Eithan.
Afiliação
  • Chai C; Goldyne Savad Institute of Gene Therapy, Hadassah Hebrew University Hospital, Jerusalem, Israel.
  • Cox B; Laboratory of Biochemical Pharmacology Emory University, Department of Pediatrics, Atlanta, Georgia.
  • Yaish D; Goldyne Savad Institute of Gene Therapy, Hadassah Hebrew University Hospital, Jerusalem, Israel.
  • Gross D; Goldyne Savad Institute of Gene Therapy, Hadassah Hebrew University Hospital, Jerusalem, Israel.
  • Rosenberg N; Goldyne Savad Institute of Gene Therapy, Hadassah Hebrew University Hospital, Jerusalem, Israel.
  • Amblard F; Laboratory of Biochemical Pharmacology Emory University, Department of Pediatrics, Atlanta, Georgia.
  • Shemuelian Z; Goldyne Savad Institute of Gene Therapy, Hadassah Hebrew University Hospital, Jerusalem, Israel.
  • Gefen M; Goldyne Savad Institute of Gene Therapy, Hadassah Hebrew University Hospital, Jerusalem, Israel.
  • Korach A; Cardiothoracic Surgery, Hadassah Hebrew University Hospital, Jerusalem, Israel.
  • Tirosh O; Institute of Biochemistry, Food Science and Nutrition, The Robert H. Smith Faculty of Agriculture, Food, and Environment, The Hebrew University of Jerusalem, Rehovot, Israel.
  • Lanton T; Goldyne Savad Institute of Gene Therapy, Hadassah Hebrew University Hospital, Jerusalem, Israel.
  • Link H; Goldyne Savad Institute of Gene Therapy, Hadassah Hebrew University Hospital, Jerusalem, Israel.
  • Tam J; Obesity and Metabolism Laboratory, Multidisciplinary Center for Cannabinoid Research, Faculty of Medicine, The Institute for Drug Research, The Hebrew University of Jerusalem, Israel.
  • Permyakova A; Obesity and Metabolism Laboratory, Multidisciplinary Center for Cannabinoid Research, Faculty of Medicine, The Institute for Drug Research, The Hebrew University of Jerusalem, Israel.
  • Ozhan G; Izmir Biomedicine and Genome Center, Dokuz Eylul University Health Campus, Izmir, Turkey.
  • Citrin J; Goldyne Savad Institute of Gene Therapy, Hadassah Hebrew University Hospital, Jerusalem, Israel.
  • Liao H; The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
  • Tannous M; Goldyne Savad Institute of Gene Therapy, Hadassah Hebrew University Hospital, Jerusalem, Israel.
  • Hahn M; Institute of Biochemistry, Food Science and Nutrition, The Robert H. Smith Faculty of Agriculture, Food, and Environment, The Hebrew University of Jerusalem, Rehovot, Israel.
  • Axelrod J; Goldyne Savad Institute of Gene Therapy, Hadassah Hebrew University Hospital, Jerusalem, Israel.
  • Arretxe E; OWL Metabolomics, Bizkaia Technology Park, Derio, Spain.
  • Alonso C; OWL Metabolomics, Bizkaia Technology Park, Derio, Spain.
  • Martinez-Arranz I; OWL Metabolomics, Bizkaia Technology Park, Derio, Spain.
  • Betés PO; OWL Metabolomics, Bizkaia Technology Park, Derio, Spain.
  • Safadi R; Liver Unit, Gastroenterology Institute, Department of Medicine, Hadassah Hebrew University Hospital, Jerusalem, Israel.
  • Salhab A; Liver Unit, Gastroenterology Institute, Department of Medicine, Hadassah Hebrew University Hospital, Jerusalem, Israel.
  • Amer J; Liver Unit, Gastroenterology Institute, Department of Medicine, Hadassah Hebrew University Hospital, Jerusalem, Israel.
  • Tber Z; Laboratory of Biochemical Pharmacology Emory University, Department of Pediatrics, Atlanta, Georgia.
  • Mengshetti S; Laboratory of Biochemical Pharmacology Emory University, Department of Pediatrics, Atlanta, Georgia.
  • Giladi H; Goldyne Savad Institute of Gene Therapy, Hadassah Hebrew University Hospital, Jerusalem, Israel.
  • Schinazi RF; Laboratory of Biochemical Pharmacology Emory University, Department of Pediatrics, Atlanta, Georgia. Electronic address: raymond.schinazi@emory.edu.
  • Galun E; Goldyne Savad Institute of Gene Therapy, Hadassah Hebrew University Hospital, Jerusalem, Israel. Electronic address: eithang@hadassah.org.il.
Gastroenterology ; 159(3): 999-1014.e9, 2020 09.
Article em En | MEDLINE | ID: mdl-32450149

Texto completo: 1 Base de dados: MEDLINE Assunto principal: MicroRNAs / Membro 1 do Grupo F da Subfamília 1 de Receptores Nucleares / Reguladores do Metabolismo de Lipídeos / Hepatopatia Gordurosa não Alcoólica / Obesidade Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: MicroRNAs / Membro 1 do Grupo F da Subfamília 1 de Receptores Nucleares / Reguladores do Metabolismo de Lipídeos / Hepatopatia Gordurosa não Alcoólica / Obesidade Idioma: En Ano de publicação: 2020 Tipo de documento: Article