MALT1 is a potential therapeutic target in glioblastoma and plays a crucial role in EGFR-induced NF-&#954;B activation.

Liu, Xuejiao; Yue, Chenglong; Shi, Lin; Liu, Guanzheng; Cao, Qiyu; Shan, Qianqian; Wang, Yifeng; Chen, Xiangyu; Li, Huan; Wang, Jie; Gao, Shangfeng; Niu, Mingshan; Yu, Rutong

MALT1 is a potential therapeutic target in glioblastoma and plays a crucial role in EGFR-induced NF-κB activation.

Liu, Xuejiao; Yue, Chenglong; Shi, Lin; Liu, Guanzheng; Cao, Qiyu; Shan, Qianqian; Wang, Yifeng; Chen, Xiangyu; Li, Huan; Wang, Jie; Gao, Shangfeng; Niu, Mingshan; Yu, Rutong.

Afiliação

Liu X; Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, China.
Yue C; Department of Neurosurgery, the Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Shi L; Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, China.
Liu G; Surgical Deparment 9, Xuzhou Children's Hospital, Xuzhou, China.
Cao Q; Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, China.
Shan Q; Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, China.
Wang Y; Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, China.
Chen X; Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, China.
Li H; Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, China.
Wang J; Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, China.
Gao S; Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, China.
Niu M; Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, China.
Yu R; Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, China.

J Cell Mol Med ; 24(13): 7550-7562, 2020 07.

Article em En | MEDLINE | ID: mdl-32452133

Assuntos

Receptores ErbB/metabolismo; Glioblastoma/metabolismo; Terapia de Alvo Molecular; Proteína de Translocação 1 do Linfoma de Tecido Linfoide Associado à Mucosa/metabolismo; NF-kappa B/metabolismo; Animais; Pontos de Checagem do Ciclo Celular/efeitos dos fármacos; Pontos de Checagem do Ciclo Celular/genética; Linhagem Celular Tumoral; Movimento Celular/efeitos dos fármacos; Movimento Celular/genética; Proliferação de Células/efeitos dos fármacos; Proliferação de Células/genética; Fator de Crescimento Epidérmico/farmacologia; Glioblastoma/patologia; Humanos; Camundongos Knockout; Proteína de Translocação 1 do Linfoma de Tecido Linfoide Associado à Mucosa/antagonistas & inibidores; Invasividade Neoplásica; Ensaio Tumoral de Célula-Tronco

Palavras-chave

EGFR/ NF-κB signalling pathway; GBM; MALT1; MI-2; cell proliferation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: NF-kappa B / Glioblastoma / Terapia de Alvo Molecular / Receptores ErbB / Proteína de Translocação 1 do Linfoma de Tecido Linfoide Associado à Mucosa Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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