<i>Polygonatum cyrtonema</i> Hua Polysaccharide Promotes GLP-1 Secretion from Enteroendocrine L-Cells through Sweet Taste Receptor-Mediated cAMP Signaling.

Xie, Song-Zi; Yang, Guang; Jiang, Xian-Min; Qin, Dan-Yang; Li, Qiang-Ming; Zha, Xue-Qiang; Pan, Li-Hua; Jin, Chuan-Shan; Luo, Jian-Ping

Polygonatum cyrtonema Hua Polysaccharide Promotes GLP-1 Secretion from Enteroendocrine L-Cells through Sweet Taste Receptor-Mediated cAMP Signaling.

Xie, Song-Zi; Yang, Guang; Jiang, Xian-Min; Qin, Dan-Yang; Li, Qiang-Ming; Zha, Xue-Qiang; Pan, Li-Hua; Jin, Chuan-Shan; Luo, Jian-Ping.

Afiliação

Xie SZ; School of Food and Biological Engineering, Hefei University of Technology, Hefei 230009, China.
Yang G; College of Pharmacy, Anhui University of Chinese Medicine, Hefei, Anhui 230012, China.
Jiang XM; School of Food and Biological Engineering, Hefei University of Technology, Hefei 230009, China.
Qin DY; School of Food and Biological Engineering, Hefei University of Technology, Hefei 230009, China.
Li QM; School of Food and Biological Engineering, Hefei University of Technology, Hefei 230009, China.
Zha XQ; School of Food and Biological Engineering, Hefei University of Technology, Hefei 230009, China.
Pan LH; School of Food and Biological Engineering, Hefei University of Technology, Hefei 230009, China.
Jin CS; School of Food and Biological Engineering, Hefei University of Technology, Hefei 230009, China.
Luo JP; College of Pharmacy, Anhui University of Chinese Medicine, Hefei, Anhui 230012, China.

J Agric Food Chem ; 68(25): 6864-6872, 2020 Jun 24.

Article em En | MEDLINE | ID: mdl-32456438

Assuntos

AMP Cíclico/metabolismo; Células Enteroendócrinas/metabolismo; Peptídeo 1 Semelhante ao Glucagon/metabolismo; Extratos Vegetais/farmacologia; Polygonatum/química; Polissacarídeos/farmacologia; Receptores Acoplados a Proteínas G/metabolismo; Animais; Células Enteroendócrinas/efeitos dos fármacos; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Ratos; Ratos Sprague-Dawley; Receptores Acoplados a Proteínas G/genética; Transdução de Sinais/efeitos dos fármacos

Palavras-chave

Polygonatum cyrtonema; cAMP signaling pathway; glucagon-like peptide-1; polysaccharide; sweet taste receptor

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Polissacarídeos / Extratos Vegetais / AMP Cíclico / Células Enteroendócrinas / Polygonatum / Receptores Acoplados a Proteínas G / Peptídeo 1 Semelhante ao Glucagon Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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