Clinical Characteristics and Management of Methamphetamine-Associated Cardiomyopathy: State-of-the-Art Review.
J Am Heart Assoc
; 9(11): e016704, 2020 06 02.
Article
em En
| MEDLINE
| ID: mdl-32468897
ABSTRACT
Methamphetamine-associated cardiomyopathy (MACM) is an increasingly recognized disease entity in the context of a rapidly spreading methamphetamine epidemic. MACM may afflict individuals with a wide range of ages and socioeconomic backgrounds. Presentations can vary greatly and may involve several complications unique to the disease. Given the public health significance of this disease, there is a relative dearth of consensus material to guide clinicians in understanding, diagnosing, and managing MACM. This review therefore aims to (1) describe pathologic mechanisms of methamphetamine as they pertain to the development, progression, and prognosis of MACM, and the potential to recover cardiac function; (2) summarize existing data from epidemiologic studies and case series in an effort to improve recognition and diagnosis of the disease; (3) guide short- and long-term management of MACM with special attention to expected or potential sequelae of the disease; and (4) highlight pivotal unanswered questions in need of urgent investigation from a public health perspective.
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Base de dados:
MEDLINE
Assunto principal:
Transtornos Relacionados ao Uso de Anfetaminas
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Coração
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Estimulantes do Sistema Nervoso Central
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Metanfetamina
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Cardiomiopatias
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article