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Is twice daily LF-rTMS a viable treatment option for treatment-resistant OCD? Results from an open-label feasibility study.
Tandt, Hannelore L N; Van de Velde, Nele; De Witte, Sara; Audenaert, Kurt; Baeken, Chris; Lemmens, Gilbert M D.
Afiliação
  • Tandt HLN; Department of Psychiatry, Ghent University Hospital, C. Heymanslaan 10, 9000, Ghent, Belgium. Hannelore.Tandt@UZGent.be.
  • Van de Velde N; Department of Psychiatry, Ghent University Hospital, C. Heymanslaan 10, 9000, Ghent, Belgium.
  • De Witte S; Department of Head and Skin-Psychiatry and Medical Psychology, Ghent University, Ghent, Belgium.
  • Audenaert K; Department of Psychiatry, Ghent University Hospital, C. Heymanslaan 10, 9000, Ghent, Belgium.
  • Baeken C; Department of Head and Skin-Psychiatry and Medical Psychology, Ghent University, Ghent, Belgium.
  • Lemmens GMD; Department of Psychiatry, Ghent University Hospital, C. Heymanslaan 10, 9000, Ghent, Belgium.
Eur Arch Psychiatry Clin Neurosci ; 271(1): 211-214, 2021 Feb.
Article em En | MEDLINE | ID: mdl-32472148
ABSTRACT
Several reports point to the beneficial effects of repetitive transcranial magnetic stimulation (rTMS) in the treatment of resistant obsessive-compulsive disorder (OCD). This study aimed to evaluate the safety and efficacy of rTMS targeting the dmPFC in the treatment of treatment-resistant OCD patients. Twelve patients received 20 sessions of low-frequency (LF) rTMS (1 Hz, 1200 pulses) in a twice daily protocol during 10 weekdays. Y-BOCS and IDS scores modestly but significantly decreased after treatment and at follow-up and HADS anxiety improved at follow-up. LF rTMS may improve OCD, anxiety, and depressive symptoms in treatment-resistant OCD and was a safe and well-tolerated treatment.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Resistência a Medicamentos / Estimulação Magnética Transcraniana / Transtorno Obsessivo-Compulsivo Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Resistência a Medicamentos / Estimulação Magnética Transcraniana / Transtorno Obsessivo-Compulsivo Idioma: En Ano de publicação: 2021 Tipo de documento: Article