HuR promotes miRNA-mediated upregulation of NFI-A protein expression in MDSCs during murine sepsis.

Bah, Isatou; Alkhateeb, Tuqa; Kumbhare, Ajinkya; Youssef, Dima; Yao, Zhi Q; Hawkin, Gregory A; McCall, Charles E; El Gazzar, Mohamed

Bah, Isatou; Alkhateeb, Tuqa; Kumbhare, Ajinkya; Youssef, Dima; Yao, Zhi Q; Hawkin, Gregory A; McCall, Charles E; El Gazzar, Mohamed.

Afiliação

Bah I; Department of Internal Medicine, East Tennessee State University College of Medicine, Johnson City, TN, 37614, USA.
Alkhateeb T; Department of Internal Medicine, East Tennessee State University College of Medicine, Johnson City, TN, 37614, USA.
Kumbhare A; Department of Internal Medicine, East Tennessee State University College of Medicine, Johnson City, TN, 37614, USA.
Youssef D; Department of Internal Medicine, East Tennessee State University College of Medicine, Johnson City, TN, 37614, USA.
Yao ZQ; Department of Internal Medicine, East Tennessee State University College of Medicine, Johnson City, TN, 37614, USA.
Hawkin GA; Department of Biochemistry and Center for Precision Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, 27157, USA.
McCall CE; Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, 27157, USA.
El Gazzar M; Department of Internal Medicine, East Tennessee State University College of Medicine, Johnson City, TN, 37614, USA. Electronic address: elgazzar@etsu.edu.

Mol Immunol ; 123: 97-105, 2020 07.

Article em En | MEDLINE | ID: mdl-32474254

Assuntos

Proteína Semelhante a ELAV 1/fisiologia; MicroRNAs/fisiologia; Células Supressoras Mieloides/metabolismo; Fatores de Transcrição NFI/genética; Sepse/genética; Animais; Células Cultivadas; Masculino; Camundongos; Camundongos Endogâmicos BALB C; MicroRNAs/genética; Células Supressoras Mieloides/patologia; Fatores de Transcrição NFI/metabolismo; Sepse/metabolismo; Sepse/patologia; Ativação Transcricional; Regulação para Cima/genética

Palavras-chave

MDSC; NFI-A; Sepsis; miRNA

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sepse / MicroRNAs / Fatores de Transcrição NFI / Proteína Semelhante a ELAV 1 / Células Supressoras Mieloides Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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