Spontaneous Axonal Dystrophy in the Brain and Spinal Cord in Naïve Beagle Dogs.

Pardo, Ingrid D; Otis, Diana; Ritenour, Hayley N; Bailey, Steven; Masek-Hammerman, Katherine; Dowty, Heather V; Bolon, Brad; Palazzi, Xavier

Pardo, Ingrid D; Otis, Diana; Ritenour, Hayley N; Bailey, Steven; Masek-Hammerman, Katherine; Dowty, Heather V; Bolon, Brad; Palazzi, Xavier.

Afiliação

Pardo ID; Global Pathology and Investigative Toxicology, Pfizer Inc, Groton, CT, USA.
Otis D; Global Pathology and Investigative Toxicology, Pfizer Inc, Groton, CT, USA.
Ritenour HN; Global Pathology and Investigative Toxicology, Pfizer Inc, Groton, CT, USA.
Bailey S; Department of Statistics, Pfizer Inc, Cambridge, MA, USA.
Masek-Hammerman K; Global Pathology and Investigative Toxicology, Pfizer Inc, Cambridge, MA, USA.
Dowty HV; Drug Safety Research and Development, Pfizer Inc, Cambridge, MA, USA.
Bolon B; GEMpath, Inc, Longmont, CO, USA.
Palazzi X; Global Pathology and Investigative Toxicology, Pfizer Inc, Groton, CT, USA.

Toxicol Pathol ; 48(5): 694-701, 2020 07.

Article em En | MEDLINE | ID: mdl-32476609

Assuntos

Encéfalo/patologia; Doenças do Cão/patologia; Distrofias Neuroaxonais/patologia; Medula Espinal/patologia; Animais; Sistema Nervoso Central/patologia; Modelos Animais de Doenças; Cães; Feminino; Masculino; Bulbo/patologia; Degeneração Neural/patologia

Palavras-chave

Beagle dog; axonal dystrophy; axonal swelling; central nervous system; neuroaxonal dystrophy; peripheral nervous system; spheroid; spontaneous finding

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Medula Espinal / Encéfalo / Distrofias Neuroaxonais / Doenças do Cão Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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