[Drug-induced restless legs syndrome]. / Lekarstvenno-indutsirovannyi sindrom bespokoinykh nog.
Zh Nevrol Psikhiatr Im S S Korsakova
; 120(4): 129-135, 2020.
Article
em Ru
| MEDLINE
| ID: mdl-32490630
ABSTRACT
Restless legs syndrome (RLS) is a sensorimotor disorder characterized by complaints of a strong desire to move legs during periods of rest or inactivity, which is relieved by movement (most pronounced in the evening or at night). Multiple studies have reported drug-induced RLS caused by antipsychotics, antidepressants and antiepileptic medications. Risk factors for drug-induced RLS include older age, gastrointestinal diseases, high medication dose, simultaneous use of ≥2 drugs. The mechanism of drug-induced RLS is most often associated with the effect of medications on various receptors and neurotransmitter systems, in particular, the dopamine system. Drug-induced RLS treatment includes identification and withdrawal of a drug that caused RLS or a decrease in its dosage. Prevention of drug-induced RLS is based on compliance with the principles of rational pharmacotherapy.
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Base de dados:
MEDLINE
Assunto principal:
Síndrome das Pernas Inquietas
Idioma:
Ru
Ano de publicação:
2020
Tipo de documento:
Article