Tuberculosis transmission across three states: The story of a solid organ donor born in an endemic country, 2018.
Transpl Infect Dis
; 22(6): e13357, 2020 Dec.
Article
em En
| MEDLINE
| ID: mdl-32510808
ABSTRACT
Transmission of tuberculosis (TB) from a deceased solid organ donor to recipients can result in severe morbidity and mortality. In 2018, four solid organ transplant recipients residing in three states but sharing a common organ donor were diagnosed with TB disease. Two recipients were hospitalized and none died. The organ donor was born in a country with a high incidence of TB and experienced 8 weeks of headache and fever prior to death, but was not tested for TB during multiple hospitalizations or prior to organ procurement. TB isolates of two organ recipients and a close contact of the donor had identical TB genotypes and closely related whole-genome sequencing results. Donors with risk factors for TB, in particular birth or residence in countries with a higher TB incidence, should be carefully evaluated for TB.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Tuberculose
/
Transplante de Órgãos
/
Mycobacterium tuberculosis
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article