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Ripretinib in patients with advanced gastrointestinal stromal tumours (INVICTUS): a double-blind, randomised, placebo-controlled, phase 3 trial.
Blay, Jean-Yves; Serrano, César; Heinrich, Michael C; Zalcberg, John; Bauer, Sebastian; Gelderblom, Hans; Schöffski, Patrick; Jones, Robin L; Attia, Steven; D'Amato, Gina; Chi, Ping; Reichardt, Peter; Meade, Julie; Shi, Kelvin; Ruiz-Soto, Rodrigo; George, Suzanne; von Mehren, Margaret.
Afiliação
  • Blay JY; Department of Medicine, Centre Léon Bérard, Lyon, France; Headquarters, Unicancer, Paris, France; LYRICAN, Lyon, France; Faculte Lyon Est, Université Claude Bernard, Lyon, France. Electronic address: jean-yves.blay@lyon.unicancer.fr.
  • Serrano C; Department of Medical Oncology, Vall d'Hebron Institute of Oncology, Barcelona, Spain.
  • Heinrich MC; Department of Medicine, Portland VA Health Care System, Portland, OR, USA; OHSU Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA.
  • Zalcberg J; Department of Epidemiology and Preventative Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; Department of Medical Oncology, Alfred Health, Melbourne, VIC, Australia.
  • Bauer S; Department of Medical Oncology, West German Cancer Center, University of Duisburg-Essen, Essen, Germany; German Consortium for Translational Cancer Research (DKTK), Partner Site Essen, Germany.
  • Gelderblom H; Department of Medical Oncology, Leiden University Medical Center, Leiden, Netherlands.
  • Schöffski P; Leuven Cancer Institute and Department of General Medical Oncology, University Hospitals Leuven, Leuven, Belgium.
  • Jones RL; Sarcoma Unit, The Royal Marsden NHS Foundation Trust, London, UK; Division of Clinical Studies, The Institute of Cancer Research, London, UK.
  • Attia S; Department of Hematology and Oncology, Mayo Clinic, Jacksonville, FL, USA.
  • D'Amato G; Sylvester Comprehensive Cancer Center, University of Miami Health System, Miami, FL, USA.
  • Chi P; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Weill Cornell Medicine, New York, NY, USA.
  • Reichardt P; Department of Oncology, Helios Klinikum Berlin-Buch, Berlin, Germany.
  • Meade J; Deciphera Pharmaceuticals, Waltham, MA, USA.
  • Shi K; Deciphera Pharmaceuticals, Waltham, MA, USA.
  • Ruiz-Soto R; Deciphera Pharmaceuticals, Waltham, MA, USA.
  • George S; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • von Mehren M; Department of Hematology and Medical Oncology, Fox Chase Cancer Center, Philadelphia, PA, USA.
Lancet Oncol ; 21(7): 923-934, 2020 07.
Article em En | MEDLINE | ID: mdl-32511981

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos de Fenilureia / Piridinas / Tumores do Estroma Gastrointestinal / Neoplasias Gastrointestinais Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos de Fenilureia / Piridinas / Tumores do Estroma Gastrointestinal / Neoplasias Gastrointestinais Idioma: En Ano de publicação: 2020 Tipo de documento: Article