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Protein kinases A and C regulate amyloid-ß degradation by modulating protein levels of neprilysin and insulin-degrading enzyme in astrocytes.
Yamamoto, Naoki; Nakazawa, Mitsuki; Nunono, Naho; Yoshida, Nao; Obuchi, Ayako; Tanida, Mamoru; Suzuki, Kenji; Ikeda-Matsuo, Yuri; Sobue, Kazuya.
Afiliação
  • Yamamoto N; Department of Pharmaceutical Health Care, Faculty of Pharmaceutical Sciences, Himeji Dokkyo University, Himeji, Hyogo, Japan; Faculty of Pharmaceutical Sciences, Hokuriku University, Kanazawa, Ishikawa, 920-1181, Japan; Laboratory of Molecular Medicinal Science, Department of Pharmacy, College of Ph
  • Nakazawa M; Laboratory of Molecular Medicinal Science, Department of Pharmacy, College of Pharmaceutical Sciences, Ritsumeikan University, Kusatsu, Shiga, 525-8577, Japan.
  • Nunono N; Laboratory of Molecular Medicinal Science, Department of Pharmacy, College of Pharmaceutical Sciences, Ritsumeikan University, Kusatsu, Shiga, 525-8577, Japan.
  • Yoshida N; Laboratory of Molecular Medicinal Science, Department of Pharmacy, College of Pharmaceutical Sciences, Ritsumeikan University, Kusatsu, Shiga, 525-8577, Japan.
  • Obuchi A; Department of Pharmaceutical Health Care, Faculty of Pharmaceutical Sciences, Himeji Dokkyo University, Himeji, Hyogo, Japan.
  • Tanida M; Department of Physiology II, Kanazawa Medical University, Uchinada, Ishikawa, 920-0293, Japan.
  • Suzuki K; Laboratory of Molecular Medicinal Science, Department of Pharmacy, College of Pharmaceutical Sciences, Ritsumeikan University, Kusatsu, Shiga, 525-8577, Japan.
  • Ikeda-Matsuo Y; Faculty of Pharmaceutical Sciences, Hokuriku University, Kanazawa, Ishikawa, 920-1181, Japan.
  • Sobue K; Department of Anesthesiology and Intensive Care Medicine, Nagoya City University Graduate School of Medical Sciences, Nagoya City, Aichi, 467-8622, Japan.
Neurosci Res ; 166: 62-72, 2021 May.
Article em En | MEDLINE | ID: mdl-32512031
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteína Quinase C / Neprilisina / Astrócitos / Peptídeos beta-Amiloides / Proteínas Quinases Dependentes de AMP Cíclico / Doença de Alzheimer / Insulisina Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteína Quinase C / Neprilisina / Astrócitos / Peptídeos beta-Amiloides / Proteínas Quinases Dependentes de AMP Cíclico / Doença de Alzheimer / Insulisina Idioma: En Ano de publicação: 2021 Tipo de documento: Article