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The effect of sample size on polygenic hazard models for prostate cancer.
Karunamuni, Roshan A; Huynh-Le, Minh-Phuong; Fan, Chun C; Eeles, Rosalind A; Easton, Douglas F; Kote-Jarai, ZSofia; Amin Al Olama, Ali; Benlloch Garcia, Sara; Muir, Kenneth; Gronberg, Henrik; Wiklund, Fredrik; Aly, Markus; Schleutker, Johanna; Sipeky, Csilla; Tammela, Teuvo L J; Nordestgaard, Børge G; Key, Tim J; Travis, Ruth C; Neal, David E; Donovan, Jenny L; Hamdy, Freddie C; Pharoah, Paul; Pashayan, Nora; Khaw, Kay-Tee; Thibodeau, Stephen N; McDonnell, Shannon K; Schaid, Daniel J; Maier, Christiane; Vogel, Walther; Luedeke, Manuel; Herkommer, Kathleen; Kibel, Adam S; Cybulski, Cezary; Wokolorczyk, Dominika; Kluzniak, Wojciech; Cannon-Albright, Lisa; Brenner, Hermann; Schöttker, Ben; Holleczek, Bernd; Park, Jong Y; Sellers, Thomas A; Lin, Hui-Yi; Slavov, Chavdar; Kaneva, Radka; Mitev, Vanio; Batra, Jyotsna; Clements, Judith A; Spurdle, Amanda; Teixeira, Manuel R; Paulo, Paula.
Afiliação
  • Karunamuni RA; Department of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, CA, USA. rakarunamuni@health.ucsd.edu.
  • Huynh-Le MP; Department of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, CA, USA.
  • Fan CC; Healthlytix, 4747 Executive Dr. Suite 820, San Diego, CA, USA.
  • Eeles RA; The Institute of Cancer Research, London, SM2 5NG, UK.
  • Easton DF; Royal Marsden NHS Foundation Trust, London, SW3 6JJ, UK.
  • Kote-Jarai Z; Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, Strangeways Research Laboratory, University of Cambridge, Cambridge, CB1 8RN, UK.
  • Amin Al Olama A; The Institute of Cancer Research, London, SM2 5NG, UK.
  • Benlloch Garcia S; Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, Strangeways Research Laboratory, University of Cambridge, Cambridge, CB1 8RN, UK.
  • Muir K; Department of Clinical Neurosciences, Stroke Research Group, R3, Box 83, Cambridge Biomedical Campus, University of Cambridge, Cambridge, CB2 0QQ, UK.
  • Gronberg H; Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, Strangeways Research Laboratory, University of Cambridge, Cambridge, CB1 8RN, UK.
  • Wiklund F; Division of Population Health, Health Services Research and Primary Care, University of Manchester, Oxford Road, Manchester, M13 9PL, UK.
  • Aly M; Warwick Medical School, University of Warwick, Coventry, UK.
  • Schleutker J; Department of Medical Epidemiology and Biostatistics, Karolinska Institute, SE-171 77, Stockholm, Sweden.
  • Sipeky C; Department of Medical Epidemiology and Biostatistics, Karolinska Institute, SE-171 77, Stockholm, Sweden.
  • Tammela TLJ; Department of Medical Epidemiology and Biostatistics, Karolinska Institute, SE-171 77, Stockholm, Sweden.
  • Nordestgaard BG; Department of Molecular Medicine and Surgery, Karolinska Institute, SE-171 77, Stockholm, Sweden.
  • Key TJ; Department of Urology, Karolinska University Hospital, Stockholm, Sweden.
  • Travis RC; Institute of Biomedicine, University of Turku, Kiinamyllynkatu 10, FI-20014, Turku, Finland.
  • Neal DE; Department of Medical Genetics, Genomics, Laboratory Division, Turku University Hospital, PO Box 52, 20521, Turku, Finland.
  • Donovan JL; Institute of Biomedicine, University of Turku, Kiinamyllynkatu 10, FI-20014, Turku, Finland.
  • Hamdy FC; Faculty of Medicine and Health Technology, Prostate Cancer Research Center, Tampere University, FI-33014, Tampere, Finland.
  • Pharoah P; Department of Urology, Tampere University Hospital, Tampere, Finland.
  • Pashayan N; Faculty of Health and Medical Sciences, University of Copenhagen, 2200, Copenhagen, Denmark.
  • Khaw KT; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, 2200, Copenhagen, Denmark.
  • Thibodeau SN; Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, OX3 7LF, UK.
  • McDonnell SK; Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, OX3 7LF, UK.
  • Schaid DJ; Nuffield Department of Surgical Sciences, University of Oxford, Room 6603, Level 6, John Radcliffe Hospital, Headley Way, Headington, Oxford, OX3 9DU, UK.
  • Maier C; Department of Oncology, Box 279, Addenbrooke's Hospital, University of Cambridge, Hills Road, Cambridge, CB2 0QQ, UK.
  • Vogel W; Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK.
  • Luedeke M; School of Social and Community Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Bristol, BS8 2PS, UK.
  • Herkommer K; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, OX1 2JD, UK.
  • Kibel AS; Faculty of Medical Science, John Radcliffe Hospital, University of Oxford, Oxford, UK.
  • Cybulski C; Department of Oncology, Centre for Cancer Genetic Epidemiology, Strangeways Laboratory, University of Cambridge, Worts Causeway, Cambridge, CB1 8RN, UK.
  • Wokolorczyk D; Department of Oncology, Centre for Cancer Genetic Epidemiology, Strangeways Laboratory, University of Cambridge, Worts Causeway, Cambridge, CB1 8RN, UK.
  • Kluzniak W; Department of Applied Health Research, University College London, London, UK.
  • Cannon-Albright L; Department of Applied Health Research, University College London, London, WC1E 7HB, UK.
  • Brenner H; Clinical Gerontology Unit, University of Cambridge, Cambridge, CB2 2QQ, UK.
  • Schöttker B; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, 55905, USA.
  • Holleczek B; Division of Biomedical Statistics & Informatics, Mayo Clinic, Rochester, MN, 55905, USA.
  • Park JY; Division of Biomedical Statistics & Informatics, Mayo Clinic, Rochester, MN, 55905, USA.
  • Sellers TA; Humangenetik Tuebingen, Paul-Ehrlich-Str 23, D-72076, Tuebingen, Germany.
  • Lin HY; Institute for Human Genetics, University Hospital Ulm, 89075, Ulm, Germany.
  • Slavov C; Humangenetik Tuebingen, Paul-Ehrlich-Str 23, D-72076, Tuebingen, Germany.
  • Kaneva R; Department of Urology, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, München, Germany.
  • Mitev V; Division of Urologic Surgery, Brigham and Womens Hospital, 75 Francis Street, Boston, MA, 02115, USA.
  • Batra J; Department of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University, 70-115, Szczecin, Poland.
  • Clements JA; Department of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University, 70-115, Szczecin, Poland.
  • Spurdle A; Department of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University, 70-115, Szczecin, Poland.
  • Teixeira MR; George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, UT, 84148, USA.
  • Paulo P; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), D-69120, Heidelberg, Germany.
Eur J Hum Genet ; 28(10): 1467-1475, 2020 10.
Article em En | MEDLINE | ID: mdl-32514134
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Herança Multifatorial / Polimorfismo de Nucleotídeo Único / Estudo de Associação Genômica Ampla Idioma: En Ano de publicação: 2020 Tipo de documento: Article
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Herança Multifatorial / Polimorfismo de Nucleotídeo Único / Estudo de Associação Genômica Ampla Idioma: En Ano de publicação: 2020 Tipo de documento: Article