Oncogenic Herpesvirus Engages Endothelial Transcription Factors SOX18 and PROX1 to Increase Viral Genome Copies and Virus Production.

Gramolelli, Silvia; Elbasani, Endrit; Tuohinto, Krista; Nurminen, Veijo; Günther, Thomas; Kallinen, Riikka E; Kaijalainen, Seppo P; Diaz, Raquel; Grundhoff, Adam; Haglund, Caj; Ziegelbauer, Joseph M; Pellinen, Teijo; Bower, Mark; Francois, Mathias; Ojala, Päivi M

Gramolelli, Silvia; Elbasani, Endrit; Tuohinto, Krista; Nurminen, Veijo; Günther, Thomas; Kallinen, Riikka E; Kaijalainen, Seppo P; Diaz, Raquel; Grundhoff, Adam; Haglund, Caj; Ziegelbauer, Joseph M; Pellinen, Teijo; Bower, Mark; Francois, Mathias; Ojala, Päivi M.

Afiliação

Gramolelli S; Translational Cancer Medicine Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Elbasani E; Translational Cancer Medicine Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Tuohinto K; Translational Cancer Medicine Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Nurminen V; Translational Cancer Medicine Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Günther T; Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg, Germany.
Kallinen RE; Translational Cancer Medicine Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Kaijalainen SP; Translational Cancer Medicine Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Diaz R; Translational Cancer Medicine Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Grundhoff A; Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg, Germany.
Haglund C; Translational Cancer Medicine Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Ziegelbauer JM; Department of Surgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Pellinen T; HIV and AIDS Malignancy Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland.
Bower M; Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland.
Francois M; National Centre for HIV Malignancy, Chelsea & Westminster Hospital, London, United Kingdom.
Ojala PM; The David Richmond Program for Cardio-Vascular Research: Gene Regulation and Editing, The Centenary Institute, The University of Sydney, Camperdown, Australia.

Cancer Res ; 80(15): 3116-3129, 2020 08 01.

Article em En | MEDLINE | ID: mdl-32518203

Assuntos

Transformação Celular Viral/genética; Herpesvirus Humano 8/fisiologia; Proteínas de Homeodomínio/fisiologia; Fatores de Transcrição SOXF/fisiologia; Sarcoma de Kaposi/genética; Proteínas Supressoras de Tumor/fisiologia; Replicação Viral/genética; Carcinogênese/genética; Células Cultivadas; Células Endoteliais/metabolismo; Células Endoteliais/patologia; Células Endoteliais/virologia; Regulação Viral da Expressão Gênica/genética; Genoma Viral/genética; Células HEK293; Herpesvirus Humano 8/genética; Herpesvirus Humano 8/patogenicidade; Proteínas de Homeodomínio/genética; Humanos; Sistema Linfático/metabolismo; Sistema Linfático/patologia; Sistema Linfático/virologia; Fatores de Transcrição SOXF/genética; Sarcoma de Kaposi/patologia; Sarcoma de Kaposi/virologia; Proteínas Supressoras de Tumor/genética

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sarcoma de Kaposi / Replicação Viral / Transformação Celular Viral / Proteínas de Homeodomínio / Herpesvirus Humano 8 / Proteínas Supressoras de Tumor / Fatores de Transcrição SOXF Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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