Perspective on CYP2C19 genotyping test among patients with acute coronary syndrome - a qualitative study.
Future Cardiol
; 16(6): 655-662, 2020 11.
Article
em En
| MEDLINE
| ID: mdl-32524842
ABSTRACT
Aim:
Identify factors patients consider regarding CYP2C19 genotyping test to guide choice of antiplatelet therapy. Patients &methods:
Patient's perception and attitude toward use of CYP2C19 genotyping test was gathered according to an interview guide. Thematic analysis was conducted.Results:
A total of 14 patients were interviewed. The main factors found to influence uptake of CYP2C19 genotyping test are, convenience of genotyping test (n = 4), physician's recommendation (n = 11), prior explanation of genetic testing by medical personnel (n = 5) and inclination toward clopidogrel, with three sub-factors; less frequent dosing (n = 3), lower cost (n = 7) and lower risk of bleeding (n = 9).Conclusion:
This study provided the information needed to develop a discrete choice experiment to empirically quantify patients' preference and willingness to pay for genetic testing and to simulate uptake.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Síndrome Coronariana Aguda
/
Intervenção Coronária Percutânea
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article