Five-year Survival Prediction and Safety Outcomes with Enzalutamide in Men with Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer from the PREVAIL Trial.

Armstrong, Andrew J; Lin, Ping; Tombal, Bertrand; Saad, Fred; Higano, Celestia S; Joshua, Anthony M; Parli, Teresa; Rosbrook, Brad; van Os, Steve; Beer, Tomasz M

Armstrong, Andrew J; Lin, Ping; Tombal, Bertrand; Saad, Fred; Higano, Celestia S; Joshua, Anthony M; Parli, Teresa; Rosbrook, Brad; van Os, Steve; Beer, Tomasz M.

Afiliação

Armstrong AJ; Division of Medical Oncology and Urology, Duke Cancer Institute, Duke University, Durham, NC, USA. Electronic address: andrew.armstrong@duke.edu.
Lin P; Biostatistics, Pfizer Inc., San Francisco, CA, USA.
Tombal B; Urology, Cliniques Universitaires Saint-Luc, Brussels, Belgium.
Saad F; Division of Urology and Urologic Oncology, Centre Hospitalier de l'Université de Montréal, Montreal, QC, Canada.
Higano CS; Medical Oncology, University of Washington and Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Joshua AM; Department of Medical Oncology, Kinghorn Cancer Centre, St Vincent's Hospital, Sydney, New South Wales, Australia.
Parli T; Clinical Development, Pfizer Inc., San Francisco, CA, USA.
Rosbrook B; Biostatistics, Pfizer Inc., San Diego, CA, USA.
van Os S; Biostatistics, Astellas Pharma Europe BV, Leiden, The Netherlands.
Beer TM; Hematology/Medical Oncology, OHSU Knight Cancer Institute Oregon Health & Science University, Portland, OR, USA.

Eur Urol ; 78(3): 347-357, 2020 09.

Article em En | MEDLINE | ID: mdl-32527692

Assuntos

Benzamidas/uso terapêutico; Nitrilas/uso terapêutico; Feniltioidantoína/uso terapêutico; Neoplasias de Próstata Resistentes à Castração/tratamento farmacológico; Idoso; Benzamidas/efeitos adversos; Estudos Cross-Over; Método Duplo-Cego; Humanos; Masculino; Nitrilas/efeitos adversos; Feniltioidantoína/efeitos adversos; Prognóstico; Análise de Sobrevida; Taxa de Sobrevida; Fatores de Tempo; Resultado do Tratamento

Palavras-chave

Enzalutamide; Metastatic castration-resistant prostate cancer; Multivariable model; Overall survival; Prostate-specific antigen; Safety

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Feniltioidantoína / Benzamidas / Neoplasias de Próstata Resistentes à Castração / Nitrilas Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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