Sericin: A Versatile Protein Biopolymer with Therapeutic Significance.
Curr Pharm Des
; 26(42): 5414-5429, 2020.
Article
em En
| MEDLINE
| ID: mdl-32532189
ABSTRACT
Sericin is a unique proteinaceous biopolymer obtained from cocoons of Bombyx Mori. It has become very popular since it is bestowed with numerous health benefits. Sericin is composed of 18 types of amino acids, out of which 8 amino acids play a significant role in human metabolic pathways. Sericin is easily amenable to make into novel dosage forms and also has been conferred with numerous therapeutic activities such as wound healing, antihypertensive, neuro-protective, antitumor, anti-diabetic, anti-wrinkle, anti-ageing and antioxidant amongst various others. This review summarizes the current status of sericin, as a therapeutic moiety with a focus on active constituents as well as their proposed mechanism in the treatment of various chronic diseases. It also summarizes previous and current in-vitro, in-vivo, cell lines studies and clinical trials based pieces of evidence corroborating the therapeutic activities of sericin.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Bombyx
/
Sericinas
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article