Blepharospasm, dry eye and extractable nuclear antigen antibodies.
J Fr Ophtalmol
; 43(7): e211-e215, 2020 Sep.
Article
em En
| MEDLINE
| ID: mdl-32532571
ABSTRACT
PURPOSE:
To study whether there is an association between benign essential blepharospasm and Sjögren's syndrome by analyzing the presence of antibodies to extractable nuclear antigens in this population.METHODS:
Seventy-two patients with benign essential blepharospasm (BEB) were included in this study. We excluded patients with hemifacial spasm or blepharospasm secondary to known corneal pathology. We recorded results of Schirmer I testing as well as levels of anti-SSA/Ro and anti-SSB/La antibodies.RESULTS:
Our study included 72 patients (144 eyes), of which 62 (86.1%) were women. The mean age was 74.3±10.73 years. The mean Schirmer I test result was 3.14±4.00mm. Five women (8% of this female population) were found to have positive anti-SSA/Ro and anti-SSB/La antibodies. Their mean age was 65.66±13.24 years, while the mean age of the antibody-negative patients was 75.42±9.27 years. There was no statistically significant difference between the Schirmer I tests of the antibody positive and negative patients.CONCLUSION:
This study demonstrates a possible association between Sjögren's syndrome and benign essential blepharospasm, justifying anti-SSA/Ro and anti-SSB/La testing in these patients.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Blefarospasmo
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Síndromes do Olho Seco
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Síndrome de Sjogren
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Anticorpos Antinucleares
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article